Global analysis of the mechanical properties of organic crystals
DP Karothu, J Mahmoud Halabi… - Angewandte Chemie …, 2022 - Wiley Online Library
Organic crystals, although widely studied, have not been considered nascent candidate
materials in engineering design. Here we summarize the mechanical properties of organic …
materials in engineering design. Here we summarize the mechanical properties of organic …
Global performance indices for dynamic crystals as organic thermal actuators
Crystal adaptronics is an emergent materials science discipline at the intersection of solid‐
state chemistry and mechanical engineering that explores the dynamic nature of …
state chemistry and mechanical engineering that explores the dynamic nature of …
Tabletability and compactibility of α-lactose monohydrate powders of different particle size. I. Experimental comparison
AS Persson, S Pazesh, G Alderborn - Pharmaceutical …, 2022 - Taylor & Francis
In this paper, two types of parameters representing tabletability and compactibility profiles of
a series of α-lactose monohydrate powders, ranging in particle size from approximately 3.5 …
a series of α-lactose monohydrate powders, ranging in particle size from approximately 3.5 …
[HTML][HTML] Predicting finite-temperature properties of crystalline carbon dioxide from first principles with quantitative accuracy
Molecular crystal structures, thermodynamics, and mechanical properties can vary
substantially with temperature, and predicting these temperature-dependencies correctly is …
substantially with temperature, and predicting these temperature-dependencies correctly is …
Finite-Temperature Mechanical Properties of Organic Molecular Crystals from Classical Molecular Simulation
The mechanical properties of crystalline materials can have an impact on different aspects of
solid dosage form design and manufacturing. Experimental determination of these quantities …
solid dosage form design and manufacturing. Experimental determination of these quantities …
[HTML][HTML] Indentation plasticity and fracture studies of organic crystals
S Mannepalli, KSRN Mangalampalli - Crystals, 2017 - mdpi.com
This review article summarizes the recent advances in measuring and understanding the
indentation-induced plastic deformation and fracture behavior of single crystals of a wide …
indentation-induced plastic deformation and fracture behavior of single crystals of a wide …
Application of instrumented nanoindentation in preformulation studies of pharmaceutical active ingredients and excipients
M Egart, B Janković, S Srčič - Acta Pharmaceutica, 2016 - hrcak.srce.hr
Sažetak Nanoindentation allows quantitative determination of a material's response to stress
such as elastic and plastic deformation or fracture tendency. Key instruments that have …
such as elastic and plastic deformation or fracture tendency. Key instruments that have …
A modern approach to the Heckel Equation: The effect of compaction pressure on the yield pressure of ibuprofen and its sodium salt
D Hooper, FC Clarke, JC Mitchell… - … of Nanomedicine and …, 2016 - gala.gre.ac.uk
Despite being heavily criticised in the literature the most widely used and accepted
compaction equation is the Heckel equation proposed by Heckel in 1961. Its presence in …
compaction equation is the Heckel equation proposed by Heckel in 1961. Its presence in …
How can single particle compression and nanoindentation contribute to the understanding of pharmaceutical powder compression?
The deformation behaviour of a powder and, thus, of the individual particles is a crucial
parameter in powder compaction and affects powder compressibility and compactibility. The …
parameter in powder compaction and affects powder compressibility and compactibility. The …
Characterisation of dry powder inhaler formulations using atomic force microscopy
C Weiss, P McLoughlin, H Cathcart - International Journal of Pharmaceutics, 2015 - Elsevier
Inhalation formulations are a popular way of treating the symptoms of respiratory diseases.
The active pharmaceutical ingredient (API) is delivered directly to the site of action within the …
The active pharmaceutical ingredient (API) is delivered directly to the site of action within the …