B cells develop from hematopoietic stem cells in the bone marrow. Once generated, they
serve multiple roles in immune regulation and host defense. However, their most important …

Immunologic marker studies of the lymphoid leukemias have greatly improved the precision
of diagnosis of these disorders by providing specific information regarding the lineage and …

The early stages of lymphoid cell formation were studied by testing the differentiative
potential of phenotypically defined subsets of CD34+ bone marrow cells. A subpopulation of …

Организм здорового человека защищается от болезнетворных агентов с помощью
разных физиологических механизмов. К числу таких защитных приспособлений …

Soon after publication of our handbook" Malignant Lymphomas Other than Hodgkin's
Disease", there were calls for a small, handy synopsis for the diagnosis of lymphoma. The …

We have recently shown that two-color analysis with fluorescein isothiocyanate (FITC)–anti-
CD38 antibody could clearly distinguish myeloma cells (plasma cells) from other …

Relapse of B-lineage acute lymphoblastic leukemia (B-ALL) after allogeneic hematopoietic
stem cell transplantation (HSCT) commonly results from the failure of a graft-versus …

During the last two decades, major progress has been made in the technology of flow
cytometry and in the availability of a large series of monoclonal antibodies against surface …

Publisher Summary This chapter focuses on two sets of molecules involved in the
proliferation and differentiation of highly purified human B lymphocytes: the molecules …

Background. End-stage renal disease (ESRD) results in increased susceptibility to
infections, impaired response to vaccination and diffuse B-cell lymphopenia. However, the …