The exclusive expression of uromodulin in the kidneys has made it an intriguing protein in
kidney and cardiovascular research. Genome-wide association studies discovered variants …

Uromodulin (or Tamm-Horsfall protein) is a glycoprotein uniquely produced in the kidney by
tubular cells of the thick ascending limb of the loop of Henle and early distal tubules. This …

Sepsis is a significant cause of mortality in hospitalized patients. Concomitant development
of acute kidney injury (AKI) increases sepsis mortality through unclear mechanisms …

Background Uromodulin is a protein made only by the kidney and released in urine,
circulating in polymerizing and nonpolymerizing forms. This protein's multiple functions …

Uromodulin (also known as Tamm–Horsfall protein) is a kidney-specific glycoprotein
secreted bidirectionally into urine and into the circulation, and it is the most abundant protein …

Rationale & Objective Uromodulin (UMOD) is the most abundant protein found in urine and
has emerged as a promising biomarker of tubule health. Circulating UMOD is also …

Uromodulin: more than a marker for chronic kidney disease pr... : Current Opinion in Nephrology
and Hypertension Uromodulin: more than a marker for chronic kidney disease progression …

Serum creatinine levels are insensitive to real-time changes in kidney function or injury.
There is a growing interest in assessing kidney injury by measuring biomarkers in body fluid …

Abstract Purpose of Review We review the role of uromodulin, a protein exclusively
expressed in the kidney, in blood pressure regulation and hypertension. Recent Findings …

Сhronic kidney Disease (CKD) is the cause of both morbidity and mortality worldwide. In
Ukraine, 12% of the population is diagnosed with CKD. Significantly worsen the quality of …