Simple Summary This review depicts the principal mechanisms involved in the process of
stromal desmoplasia characterizing pancreatic ductal adenocarcinoma (PDAC). The aim of …

Mesenchymal stem cells (MSCs), as an undifferentiated group of adult multipotent cells,
have remarkable antitumor features that bring them up as a novel choice to treat cancers …

Mesenchymal stem cell (MSC) therapy has been proven to be a potentially effective
approach for idiopathic pulmonary fibrosis (IPF) treatment. However, this strategy is currently …

Mesenchymal stem cells (MSCs) have a tumor-homing ability—they accumulate inside
tumors after systemic injection, and may thus be useful as carriers for tumor-targeting …

Introduction Drug delivery to solid tumors remains a significant therapeutic challenge.
Mesenchymal stem/stromal cells (MSCs) home to tumor tissues and can be employed as …

Despite the emergence of cutting-edge therapeutic strategies and tremendous progress in
research, a complete cure of glioma remains elusive. The heterogenous nature of tumor …

The clinical translation of stem cells and their extracellular vesicles (EVs)-based therapy for
central nervous system (CNS) diseases is booming. Nevertheless, the insufficient CNS …

Glioblastoma multiforme (GBM) is the most common and aggressive form of the primary
brain tumors in humans. The intricate pathophysiology, the development of resistance by …

We review the challenges of next-generation therapeutics for both systemic and localised
delivery to brain tumours and discuss how recent engineering advances may be used to …

Mesenchymal stem cells (MSCs) can be isolated from bone marrow or other adult tissues
(adipose tissue, dental pulp, amniotic fluid, and umbilical cord). In vitro, MSCs grow as …