[HTML][HTML] Putative target sites in synganglion for novel ixodid tick control strategies

J Waldman, GM Klafke, L Tirloni, C Logullo… - Ticks and tick-borne …, 2023 - Elsevier
Acaricide resistance is a global problem that has impacts worldwide. Tick populations with
broad resistance to all commercially available acaricides have been reported. Since …

Managing fuels and fluids: Network integration of osmoregulatory and metabolic hormonal circuits in the polymodal control of homeostasis in insects

T Koyama, DW Rana, KV Halberg - BioEssays, 2023 - Wiley Online Library
Osmoregulation in insects is an essential process whereby changes in hemolymph osmotic
pressure induce the release of diuretic or antidiuretic hormones to recruit individual …

Neuropeptides in Rhipicephalus microplus and other hard ticks

J Waldman, MA Xavier, LR Vieira, R Logullo… - Ticks and tick-borne …, 2022 - Elsevier
The synganglion is the central nervous system of ticks and, as such, controls tick physiology.
It does so through the production and release of signaling molecules, many of which are …

A fluorescently-tagged tick kinin neuropeptide triggers peristalsis and labels tick midgut muscles

JR Hernandez, C Xiong, PV Pietrantonio - Scientific Reports, 2024 - nature.com
Ticks are blood-feeding arthropods that require heme for their successful reproduction.
During feeding they also acquire pathogens that are subsequently transmitted to humans …

AI protein structure prediction-based modeling and mutagenesis of a protostome receptor and peptide ligands reveal key residues for their interaction

SQ Guo, YD Li, P Chen, G Zhang, HY Wang… - Journal of Biological …, 2022 - ASBMB
The protostome leucokinin (LK) signaling system, including LK peptides and their G protein-
coupled receptors, has been characterized in several species. Despite the progress …

Identification of Neuropeptides and Their Receptors in the Ectoparasitoid, Habrobracon hebetor

K Yu, S Xiong, G Xu, X Ye, H Yao, F Wang… - Frontiers in …, 2020 - frontiersin.org
Neuropeptides are a group of signal molecules that regulate many physiological and
behavioral processes by binding to corresponding receptors, most of which are G-protein …

Proteomic profiling of plasma-derived small extracellular vesicles: a novel tool for understanding the systemic effects of tick burden in cattle

N Turner, P Abeysinghe, H Peiris… - Journal of Animal …, 2022 - academic.oup.com
Cattle ticks pose a significant threat to the health and profitability of cattle herds globally. The
investigation of factors leading to natural tick resistance in cattle is directed toward targeted …

A random small molecule library screen identifies novel antagonists of the kinin receptor from the cattle fever tick, Rhipicephalus microplus (Acari: Ixodidae)

C Xiong, D Baker, PV Pietrantonio - Pest Management Science, 2021 - Wiley Online Library
BACKGROUND The southern cattle tick, Rhipicephalus microplus, is a primary vector of the
deadly bovine disease babesiosis. Worldwide populations of ticks have developed …

De novo assembly and analysis of the transcriptome of the Dermacentor marginatus genes differentially expressed after blood-feeding and long-term starvation

E Hu, Y Meng, Y Ma, R Song, Z Hu, M Li, Y Hao… - Parasites & …, 2020 - Springer
Abstract Background The ixodid tick Dermacentor marginatus is a vector of many pathogens
wide spread in Eurasia. Studies of gene sequence on many tick species have greatly …

Leucokinins: multifunctional neuropeptides and hormones in insects and other invertebrates

DR Nässel, SF Wu - International Journal of Molecular Sciences, 2021 - mdpi.com
Leucokinins (LKs) constitute a neuropeptide family first discovered in a cockroach and later
identified in numerous insects and several other invertebrates. The LK receptors are only …