Regulatory T (Treg) cells represent a distinct lineage of cells of the adaptive immune system
indispensable for forestalling fatal autoimmune and inflammatory pathologies. The role of …

Interferon-gamma (IFN-γ) is a pleiotropic molecule with associated antiproliferative, pro-
apoptotic and antitumor mechanisms. This effector cytokine, often considered as a major …

Tregs not only keep immune responses to autoantigens in check, but also restrain those
directed toward pathogens and the commensal microbiota. Control of peripheral immune …

The function of regulatory T cells (Treg cells) has been attributed to a growing number of
diverse pathways, molecules and processes. Seemingly contradictory conclusions …

Using a model of lethal oral infection with Toxoplasma gondii, we examined the fate of both
induced and natural regulatory T (Treg) cells in the face of strong inflammatory responses …

Summary Uncommitted (naive) murine CD4+ T helper cells (Thp) can be induced to
differentiate towards T helper 1 (Th1), Th2, Th17 and regulatory (Treg) phenotypes …

In amyotrophic lateral sclerosis (ALS), immune cells and glia contribute to motor neuron
(MN) degeneration. We report the presence of NK cells in post-mortem ALS motor cortex …

Specific therapy with modulated DC may restore immunological tolerance, thereby obviating
the need for chronic immunosuppression in transplantation or autoimmunity. In this study we …

В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

Although interferon γ (IFN-γ) secretion is essential for control of most intracellular pathogens,
host survival often also depends on the expression of interleukin 10 (IL-10), a cytokine …