Recent application of Raman spectroscopy in tumor diagnosis: from conventional methods to artificial intelligence fusion

Y Qi, Y Liu, J Luo - PhotoniX, 2023 - Springer
Raman spectroscopy, as a label-free optical technology, has widely applied in tumor
diagnosis. Relying on the different Raman technologies, conventional diagnostic methods …

Raman spectroscopy: a tool for molecular fingerprinting of brain cancer

S Murugappan, SAM Tofail, ND Thorat - ACS omega, 2023 - ACS Publications
Brain cancer is one of those few cancers with very high mortality and low five-year survival
rate. First and foremost reason for the woes is the difficulty in diagnosing and monitoring the …

Streamlined intraoperative brain tumor classification and molecular subtyping in stereotactic biopsies using stimulated Raman histology and deep learning

D Reinecke, D Ruess, AK Meissner… - Clinical Cancer …, 2024 - aacrjournals.org
Purpose: Recent artificial intelligence algorithms aided intraoperative decision-making via
stimulated Raman histology (SRH) during craniotomy. This study assesses deep learning …

Surgical treatment of glioblastoma: State-of-the-art and future trends

AHA Sales, J Beck, O Schnell, C Fung, B Meyer… - Journal of Clinical …, 2022 - mdpi.com
Glioblastoma (GBM) is a highly aggressive disease and is associated with poor prognosis
despite treatment advances in recent years. Surgical resection of tumor remains the main …

[HTML][HTML] Virtual staining of non-fixed tissue histology

N Pillar, Y Li, Y Zhang, A Ozcan - Modern Pathology, 2024 - Elsevier
Surgical pathology workflow involves multiple labor-intensive steps, such as tissue removal,
fixation, embedding, sectioning, staining, and microscopic examination. This process is time …

Advances, technological innovations, and future prospects in stereotactic brain biopsies

A Bex, B Mathon - Neurosurgical Review, 2022 - Springer
Stereotactic brain biopsy is one of the most frequently performed brain surgeries. This
review aimed to expose the latest cutting-edge and updated technologies and innovations …

Stimulated Raman histology for histological evaluation of oral squamous cell carcinoma

D Steybe, P Poxleitner, MC Metzger… - Clinical Oral …, 2023 - Springer
Objectives To investigate whether in patients undergoing surgery for oral squamous cell
carcinoma, stimulated Raman histology (SRH), in comparison with H&E-stained frozen …

Stimulated Raman histology in the neurosurgical workflow of a major European neurosurgical center—part A

N Neidert, J Straehle, D Erny, V Sacalean… - Neurosurgical …, 2022 - Springer
Histopathological diagnosis is the current standard for the classification of brain and spine
tumors. Raman spectroscopy has been reported to allow fast and easy intraoperative tissue …

Intraoperative microscopic autofluorescence detection and characterization in brain tumors using stimulated Raman histology and two-photon fluorescence

G Fürtjes, D Reinecke, N von Spreckelsen… - Frontiers in …, 2023 - frontiersin.org
Introduction The intrinsic autofluorescence of biological tissues interferes with the detection
of fluorophores administered for fluorescence guidance, an emerging auxiliary technique in …

Toward digital histopathological assessment in surgery for central nervous system tumors using stimulated Raman histology

LI Wadiura, B Kiesel, T Roetzer-Pejrimovsky… - Neurosurgical …, 2022 - thejns.org
OBJECTIVE Intraoperative neuropathological assessment with conventional frozen sections
supports the neurosurgeon in optimizing the surgical strategy. However, preparation and …