Biomedical applications of nanomaterials in the advancement of nucleic acid therapy: mechanistic challenges, delivery strategies, and therapeutic applications

K Yadav, KK Sahu, SPE Gnanakani, P Sure… - International Journal of …, 2023 - Elsevier
In the past few decades, substantial advancement has been made in nucleic acid (NA)-
based therapies. Promising treatments include mRNA, siRNA, miRNA, and anti-sense DNA …

The energetic and physical concept of gold nanorod-dependent fluorescence in cancer treatment and development of new photonic compounds| review

DM Alshangiti, MM Ghobashy, HA Alqahtani… - RSC …, 2023 - pubs.rsc.org
The optical features of gold nanorods (GNR) may be precisely controlled by manipulating
their size, shape, and aspect ratio. This review explores the impact of these parameters on …

[HTML][HTML] Gold nanoparticles and breast cancer: a bibliometric analysis of the current state of research and future directions

Y Bustanji, J Taneera, MH Semreen, E Abu-Gharbieh… - OpenNano, 2023 - Elsevier
Gold nanoparticles (GNPs) are widely searched for their usage in breast cancer research
because of their unique features. For example, these particles can deliver drugs to specific …

Protective effect of hesperidin-loaded selenium nanoparticles stabilized by chitosan on glutamate-induced toxicity in PC12 cells

Z Najafi, E Einafshar, F Mirzavi, H Amiri… - Journal of Nanoparticle …, 2023 - Springer
Hesperidin as a natural flavonoid has a wide range of beneficial properties such as anti-
oxidant, anti-cancer, and anti-inflammatory effects. However, low water solubility and low …

Novel paradigm of therapeutic intervention for skin cancer: challenges and opportunities

M Nasim, M Khan, R Parveen, A Gull, S Khan… - Future Journal of …, 2024 - Springer
Background Skin cancer continues to be an imperative global health issue, urging
continuous exploration of treatment methodologies. Conventional treatments for skin cancer …

Differential regulation of radio-sensitivity/macrophage polarization in intestinal tissue and colorectal cancer for the optimized preoperative radiotherapy

M Zhu, Y Ren, H Zhou, L Guo, H Zhang, T Yang… - Chemical Engineering …, 2024 - Elsevier
Surgery is the preferred treatment for colorectal cancer, and the preoperative radiotherapy
(pre-RT) improves surgical success and postoperative quality of life for patients. However …

Enhancing radiotherapy for melanoma: the promise of high-Z metal nanoparticles in radiosensitization

A Bemidinezhad, S Radmehr, N Moosaei, Z Efati… - …, 2024 - Taylor & Francis
Melanoma is a type of skin cancer that can be challenging to treat, especially in advanced
stages. Radiotherapy is one of the main treatment modalities for melanoma, but its efficacy …

Application of High-Z Nanoparticles to Enhance Current Radiotherapy Treatment

N Jackson, D Cecchi, W Beckham, DB Chithrani - Molecules, 2024 - mdpi.com
Radiotherapy is an essential component of the treatment regimens for many cancer patients.
Despite recent technological advancements to improve dose delivery techniques, the dose …

Anticancer Effects of Beta-Cyclodextrin-Graphene Oxide Nanoparticles Loaded with Selenium on Human Malignant Glioblastoma Cells

M Kazemian Kakhki, F Mirzavi, M Jalili-Nik, E Einafshar… - BioNanoScience, 2024 - Springer
Glioblastoma multiforme (GBM) is among the most aggressive cancers, with substantial
metastasis potential. Here, we investigated the impact of graphene oxide nanoparticles …

[HTML][HTML] Leveraging high-throughput screening technologies in targeted mRNA delivery

Y Zhang, Z Gao, X Yang, Q Xu, Y Lu - Materials Today Bio, 2024 - Elsevier
Messenger ribonucleic acid (mRNA) has emerged as a promising molecular preventive and
therapeutic approach that opens new avenues for healthcare. Although the use of delivery …