RENEB Inter-laboratory comparison 2021: Inter-assay comparison of eight dosimetry assays

M Port, JF Barquinero, D Endesfelder… - Radiation …, 2023 - meridian.allenpress.com
Tools for radiation exposure reconstruction are required to support the medical management
of radiation victims in radiological or nuclear incidents. Different biological and physical …

[HTML][HTML] Objectives and Achievements of the HUMN project on its 26th Anniversary

M Fenech, N Holland, E Zeiger, PW Chang… - … Research-Reviews in …, 2024 - Elsevier
Micronuclei (MN) are a nuclear abnormality that occurs when chromosome fragments or
whole chromosomes are not properly segregated during mitosis and consequently are …

RENEB inter-laboratory comparison 2021: the dicentric chromosome assay

D Endesfelder, U Oestreicher, M Bucher… - Radiation …, 2023 - meridian.allenpress.com
After large-scale radiation accidents where many individuals are suspected to be exposed to
ionizing radiation, biological and physical retrospective dosimetry assays are important tools …

Exploring cytokinesis block micronucleus assay in Croatia: A journey through the past, present, and future in biomonitoring of the general population

G Gajski, V Kašuba, M Milić, M Gerić, K Matković… - … -Genetic Toxicology and …, 2024 - Elsevier
In this study, we used the cytokinesis-block micronucleus (CBMN) assay to evaluate the
background frequency of cytogenetic damage in peripheral blood lymphocytes of the …

[HTML][HTML] The Relationship between Telomere Length and Nucleoplasmic Bridges and Severity of Disease in Prostate Cancer Patients

VS Dhillon, P Deo, M Fenech - Cancers, 2023 - mdpi.com
Simple Summary Telomeres are essential to prevent telomere end fusions that cause the
formation of dicentric chromosomes and nucleoplasmic bridges (NPBs) which in turn induce …

[HTML][HTML] Comparison of Isolated Lymphocyte and Whole Blood-Based CBMN Assays for Radiation Triage

A Bertucci, RC Wilkins, S Lachapelle… - … and Genome Research, 2023 - karger.com
Following a mass-casualty nuclear/radiological event, there will be an important need for
rapid and accurate estimation of absorbed dose for biological triage. The cytokinesis-block …

[HTML][HTML] BAX and DDB2 as biomarkers for acute radiation exposure in the human blood ex vivo and non-human primate models

K Kanagaraj, MA Phillippi, EH Ober, I Shuryak… - Scientific Reports, 2024 - nature.com
There are currently no available FDA-cleared biodosimetry tools for rapid and accurate
assessment of absorbed radiation dose following a radiation/nuclear incident. Previously we …

What we have learned from RENEB inter-laboratory comparisons since 2012 with focus on ILC 2021

D Endesfelder, U Oestreicher… - Radiation …, 2023 - meridian.allenpress.com
Inter-laboratory exercises are important tools within the European network for biological
dosimetry and physical retrospective dosimetry (RENEB) to validate and improve the …

RABiT-III: an Automated Micronucleus Assay at a Non-Specialized Biodosimetry Facility

M Repin, G Garty, RJ Garippa… - Radiation …, 2024 - meridian.allenpress.com
Micronuclei, detected through the cytokinesis-block micronucleus assay, are valuable
indicators of ionizing radiation exposure, especially in short-term lymphocyte cultures. The …

FDXR gene expression and micronucleus frequency in Type 2 diabetes mellitus patients and their importance in case of radiation exposures

AS Shravani, R Priyanka, AN Indumathi, P Kamarthy… - Gene Reports, 2024 - Elsevier
Abstract Analysis of gene expression (eg Ferredoxin Reductase: FDXR) changes in the
blood samples have shown potential as predictive markers of disease, prognosis for therapy …