[HTML][HTML] Prevention strategies of postoperative adhesion in soft tissues by applying biomaterials: Based on the mechanisms of occurrence and development of …

J Liao, X Li, Y Fan - Bioactive Materials, 2023 - Elsevier
Postoperative adhesion (POA) widely occurs in soft tissues and usually leads to chronic
pain, dysfunction of adjacent organs and some acute complications, seriously reducing …

Establishments and evaluations of post‐operative adhesion animal models

Y Wang, W Zhai, L Yang, S Cheng… - Advanced …, 2023 - Wiley Online Library
After abdominopelvic surgery, there are 90–93% of patients who develop postoperative
adhesions. Post‐operative adhesions can occur after various surgical procedures, which not …

[HTML][HTML] A review of physiological and cellular mechanisms underlying fibrotic postoperative adhesion

Q Hu, X Xia, X Kang, P Song, Z Liu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Postoperative adhesions (PA) are fibrotic tissues that are the most common driver of long-
term morbidity after abdominal and pelvic surgery. The optimal drug or material to prevent …

Techniques for navigating postsurgical adhesions: Insights into mechanisms and future directions

J Chen, X Tang, Z Wang, A Perez, B Yao… - Bioengineering & …, 2023 - Wiley Online Library
Postsurgical adhesions are a common complication of surgical procedures that can lead to
postoperative pain, bowel obstruction, infertility, as well as complications with future …

Melatonin: the dawning of a treatment for fibrosis?

W Hu, Z Ma, S Jiang, C Fan, C Deng… - Journal of Pineal …, 2016 - Wiley Online Library
Fibrosis is a common occurrence following organ injury and failure. To date, there is no
effective treatment for this condition. Melatonin targets numerous molecular pathways, a …

Predisposing factors to post-operative adhesion development

CN Fortin, GM Saed, MP Diamond - Human reproduction update, 2015 - academic.oup.com
BACKGROUND Adhesion development is the most common sequelae of intra-abdominal
and pelvic surgery and represents a significant, yet poorly understood, cause of morbidity …

A ROS-responsive and scavenging hydrogel for postoperative abdominal adhesion prevention

T Zhang, Y Huang, Y Gong, X Shi, D Xiao, L Ren… - Acta Biomaterialia, 2024 - Elsevier
Postoperative abdominal adhesion (PAA) widely occurs after abdominal surgery, which
often produces severe complications. However, there were still no satisfactory anti-adhesive …

Pleiotropic roles of melatonin in endometriosis, recurrent spontaneous abortion, and polycystic ovary syndrome

HL Yang, WJ Zhou, CJ Gu, YH Meng… - American Journal of …, 2018 - Wiley Online Library
Melatonin is a neurohormone synthesized from the aromatic amino acid tryptophan mainly
by the pineal gland of mammals. Melatonin acts as a broad‐spectrum antioxidant, powerful …

Uterine fibroids are characterized by an impaired antioxidant cellular system: potential role of hypoxia in the pathophysiology of uterine fibroids

NM Fletcher, MG Saed, HM Abu-Soud… - Journal of assisted …, 2013 - Springer
Purpose Fibroids are the most common smooth muscle overgrowth in women. This study
determined the expression and the effect of hypoxia on two potent antioxidant enzymes …

Peritoneal adhesions in human and veterinary medicine: from pathogenesis to therapy. A review

A Rizzo, M Spedicato, M Mutinati, G Minoia… - …, 2010 - Taylor & Francis
Any peritoneal inflammatory process consequent to infections or surgical injuries may
induce abdominal adhesion formation. Peritoneal adhesions are connective laciniae that …