Cardiac fibrosis

NG Frangogiannis - Cardiovascular research, 2021 - academic.oup.com
Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of
extracellular matrix proteins, is a common pathophysiologic companion of many different …

[HTML][HTML] Abiotic stress in crop production

R Kopecká, M Kameniarová, M Černý… - International Journal of …, 2023 - mdpi.com
The vast majority of agricultural land undergoes abiotic stress that can significantly reduce
agricultural yields. Understanding the mechanisms of plant defenses against stresses and …

The calcium‐dependent protein kinase ZmCDPK7 functions in heat‐stress tolerance in maize

Y Zhao, H Du, Y Wang, H Wang, S Yang… - Journal of Integrative …, 2021 - Wiley Online Library
Global warming poses a serious threat to crops. Calcium‐dependent protein kinases
(CDPKs)/CPKs play vital roles in plant stress responses, but their exact roles in plant …

[HTML][HTML] Exosomes and exosomal cargos: a promising world for ventricular remodeling following myocardial infarction

J Fang, Y Zhang, D Chen, Y Zheng… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Exosomes are a pluripotent group of extracellular nanovesicles secreted by all cells that
mediate intercellular communications. The effective information within exosomes is primarily …

Lipocalin 10 is essential for protection against inflammation-triggered vascular leakage by activating LDL receptor-related protein 2-slingshot homologue 1 signalling …

H Zhao, P Wang, X Wang, W Du, HH Yang… - Cardiovascular …, 2023 - academic.oup.com
Aims Systemic inflammation occurs commonly during many human disease settings and
increases vascular permeability, leading to organ failure, and lethal outcomes. Lipocalin 10 …

[HTML][HTML] Disrupted cardiac fibroblast BCAA catabolism contributes to diabetic cardiomyopathy via a periostin/NAP1L2/SIRT3 axis

QB Lu, X Fu, Y Liu, ZC Wang, SY Liu, YC Li… - Cellular & Molecular …, 2023 - Springer
Background Periostin is an extracellular matrix protein that plays a critical role in cell fate
determination and tissue remodeling, but the underlying role and mechanism of periostin in …

[HTML][HTML] Neural functions of small heat shock proteins

T de Los Reyes, S Casas-Tintó - Neural regeneration research, 2022 - journals.lww.com
Stress response is a cellular widespread mechanism encoded by a common protein
program composed by multiple cellular factors that converge in a defense reaction to protect …

[HTML][HTML] Unbiased differential proteomic profiling between cancer-associated fibroblasts and cancer cell lines

R Lau, L Yu, TI Roumeliotis, A Stewart, L Pickard… - Journal of …, 2023 - Elsevier
Cancer-associated fibroblasts (CAFs) are a key component of tumors. We aimed to profile
the proteome of cancer cell lines representing three common cancer types (lung, colorectal …

Tissue-specific small heat shock protein 20 activation is not associated with traditional autophagy markers in Ossabaw swine with cardiometabolic heart failure

KAS Silva, EV Leary, TD Olver… - American Journal …, 2020 - journals.physiology.org
The small heat shock protein 20 (HSPB6) emerges as a potential upstream mediator of
autophagy. Although autophagy is linked to several clinical disorders, how HSPB6 and …

[HTML][HTML] Phosphorylation modifications regulating cardiac protein quality control mechanisms

S Mishra, BL Dunkerly-Eyring, G Keceli… - Frontiers in …, 2020 - frontiersin.org
Many forms of cardiac disease, including heart failure, present with inadequate protein
quality control (PQC). Pathological conditions often involve impaired removal of terminally …