Cardiac fibrosis
NG Frangogiannis - Cardiovascular research, 2021 - academic.oup.com
Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of
extracellular matrix proteins, is a common pathophysiologic companion of many different …
extracellular matrix proteins, is a common pathophysiologic companion of many different …
[HTML][HTML] Abiotic stress in crop production
R Kopecká, M Kameniarová, M Černý… - International Journal of …, 2023 - mdpi.com
The vast majority of agricultural land undergoes abiotic stress that can significantly reduce
agricultural yields. Understanding the mechanisms of plant defenses against stresses and …
agricultural yields. Understanding the mechanisms of plant defenses against stresses and …
The calcium‐dependent protein kinase ZmCDPK7 functions in heat‐stress tolerance in maize
Y Zhao, H Du, Y Wang, H Wang, S Yang… - Journal of Integrative …, 2021 - Wiley Online Library
Global warming poses a serious threat to crops. Calcium‐dependent protein kinases
(CDPKs)/CPKs play vital roles in plant stress responses, but their exact roles in plant …
(CDPKs)/CPKs play vital roles in plant stress responses, but their exact roles in plant …
[HTML][HTML] Exosomes and exosomal cargos: a promising world for ventricular remodeling following myocardial infarction
J Fang, Y Zhang, D Chen, Y Zheng… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Exosomes are a pluripotent group of extracellular nanovesicles secreted by all cells that
mediate intercellular communications. The effective information within exosomes is primarily …
mediate intercellular communications. The effective information within exosomes is primarily …
Lipocalin 10 is essential for protection against inflammation-triggered vascular leakage by activating LDL receptor-related protein 2-slingshot homologue 1 signalling …
H Zhao, P Wang, X Wang, W Du, HH Yang… - Cardiovascular …, 2023 - academic.oup.com
Aims Systemic inflammation occurs commonly during many human disease settings and
increases vascular permeability, leading to organ failure, and lethal outcomes. Lipocalin 10 …
increases vascular permeability, leading to organ failure, and lethal outcomes. Lipocalin 10 …
[HTML][HTML] Disrupted cardiac fibroblast BCAA catabolism contributes to diabetic cardiomyopathy via a periostin/NAP1L2/SIRT3 axis
QB Lu, X Fu, Y Liu, ZC Wang, SY Liu, YC Li… - Cellular & Molecular …, 2023 - Springer
Background Periostin is an extracellular matrix protein that plays a critical role in cell fate
determination and tissue remodeling, but the underlying role and mechanism of periostin in …
determination and tissue remodeling, but the underlying role and mechanism of periostin in …
[HTML][HTML] Neural functions of small heat shock proteins
T de Los Reyes, S Casas-Tintó - Neural regeneration research, 2022 - journals.lww.com
Stress response is a cellular widespread mechanism encoded by a common protein
program composed by multiple cellular factors that converge in a defense reaction to protect …
program composed by multiple cellular factors that converge in a defense reaction to protect …
[HTML][HTML] Unbiased differential proteomic profiling between cancer-associated fibroblasts and cancer cell lines
R Lau, L Yu, TI Roumeliotis, A Stewart, L Pickard… - Journal of …, 2023 - Elsevier
Cancer-associated fibroblasts (CAFs) are a key component of tumors. We aimed to profile
the proteome of cancer cell lines representing three common cancer types (lung, colorectal …
the proteome of cancer cell lines representing three common cancer types (lung, colorectal …
Tissue-specific small heat shock protein 20 activation is not associated with traditional autophagy markers in Ossabaw swine with cardiometabolic heart failure
The small heat shock protein 20 (HSPB6) emerges as a potential upstream mediator of
autophagy. Although autophagy is linked to several clinical disorders, how HSPB6 and …
autophagy. Although autophagy is linked to several clinical disorders, how HSPB6 and …
[HTML][HTML] Phosphorylation modifications regulating cardiac protein quality control mechanisms
Many forms of cardiac disease, including heart failure, present with inadequate protein
quality control (PQC). Pathological conditions often involve impaired removal of terminally …
quality control (PQC). Pathological conditions often involve impaired removal of terminally …