Metabolic processes play a critical role in immune regulation. Metabolomics is the
systematic analysis of small molecules (metabolites) in organisms or biological samples …

Influenza virus infections are a leading cause of morbidity and mortality worldwide. This is
due in part to the continual emergence of new viral variants and to synergistic interactions …

Influenza A viruses cause severe respiratory illnesses in humans and animals. Overreaction
of the innate immune response to influenza virus infection results in hypercytokinemia …

The SARS-CoV-2 virus disproportionately causes serious illness and death in older
individuals. In order to have the greatest impact in decreasing the human toll caused by the …

Background Age> 65 years is a key risk factor for poor outcomes after human influenza
infection. Specifically, in addition to respiratory disease, non-neurotropic influenza A virus …

Influenza is a respiratory virus that alone or in combination with secondary bacterial
pathogens can contribute to the development of acute pneumonia in persons> 65 years of …

Increased susceptibility to the serious complications of influenza is common in older adults.
It is often ascribed to weakening of the immune system with age, and 90% of influenza …

The COVID-19 crisis has shown that classic sequential models for scientific research are too
slow and do not easily encourage multidisciplinary scientific collaboration. The need to …

Respiratory syncytial virus can cause severe illness and even death, particularly in infants.
The increased severity of disease in young children is thought to be due to a lack of previous …

Background: Influenza is a common viral condition, but factors related to short-term mortality
have not been fully studied in older adults. Our objective was to determine whether there is …