In situ ATR-IR spectroscopy has been applied to the study of glutamic (Glu) and aspartic
(Asp) acid adsorbed on amorphous TiO2 particle films. Unlike Asp, which gives evidence of …

Clotting and thrombosis remain the most serious problems in the development of blood
contacting devices such as heart valves, vascular stents, grafts and catheters. No material …

Covalent antithrombin–heparin complex (ATH) was covalently grafted to a polycarbonate
urethane (Corethane®) endoluminal graft (a kind gift of Corvita Corporation) after being …

Surface modification is an effective way to improve the hemocompatibility and remain bulk
properties of biomaterials. Recently, polymer tailed with zwitterions was found having good …

Platelet adhesion and protein adsorption on the silicone rubber film grafted with N, N′-
dimethyl-N-methacryloyloxyethyl-N-(2-carboxyethyl) ammonium (DMMCA) was studied. The …

Protein adsorption is an important phenomenon influencing the cellular response to
biomaterials. Previous studies comparing monocyte activation on a degradable polar …

In this work the hypothesis that a mature, cross-linked fibrin clot, pre-formed on a
biomaterial, may be relatively nonthrombogenic was investigated. A cross-linked fibrin layer …

The adsorption of plasminogen, the principal protein of the fibrinolytic pathway in blood, to a
number of solid surfaces from plasma was investigated. This study forms part of a larger …

The adsorption of fibrinogen and plasminogen from plasma to silica glass, sulfonated silica
glass, and lysinederivatized silica glass has been investigated. The data indicate that the …

The ability of plasminogen adsorbed from buffer onto sulphonated silica glass or lysine-
derivatized silica glass to lyse fibrin I clots has been investigated. Clots were formed around …