Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of the motor pathways,
invariably leading to death within a few years of onset. Most cases of ALS are sporadic, but …

Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are
neurodegenerative diseases with clinical and pathological overlap. Landmark discoveries of …

Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. The neuropathology associated with most FTD is characterized by abnormal cellular …

The development of our understanding of frontotemporal dementia (FTD) has gathered pace
over the last 10 years. After taking a back seat to A lzheimer's disease for many years FTD …

Cytogenetics of Bone and Soft Tissue Tumors [1]. In view of the remarkable developments in
this field since 1994, both in the cytogenetic and particularly in the molecular genetic …

Abstract Background FUS, EWS and TAF15 are structurally similar multifunctional proteins
that were first discovered upon characterization of fusion oncogenes in human sarcomas …

The gene FUS (also known as TLS (for translocated in liposarcoma) and hnRNP P 2) is
translocated with the gene encoding the transcription factor ERG-1 in human myeloid …

Ewing's sarcoma is a highly aggressive bone and soft tissue tumor of children and young
adults. At the molecular genetic level Ewing's sarcoma is characterized by a balanced …

Abstract Purpose: A specific TLS-CHOP fusion gene resulting from the t (12; 16) is present in
at least 95% of myxoid liposarcomas (MLS). Three common forms of the TLS-CHOP fusion …

microRNA abundance has been shown to depend on the amount of the microprocessor
components or, in some cases, on specific auxiliary co‐factors. In this paper, we show that …