[HTML][HTML] The role of selenium in pathologies: an updated review

G Barchielli, A Capperucci, D Tanini - Antioxidants, 2022 - mdpi.com
Selenium is an essential microelement required for a number of biological functions.
Selenium—and more specifically the amino acid selenocysteine—is present in at least 25 …

The role of glutathione peroxidase-1 in health and disease

DE Handy, J Loscalzo - Free Radical Biology and Medicine, 2022 - Elsevier
Abstract Glutathione peroxidase 1 (GPx1) is an important cellular antioxidant enzyme that is
found in the cytoplasm and mitochondria of mammalian cells. Like most selenoenzymes, it …

[HTML][HTML] The impact of selenium deficiency on cardiovascular function

BK Shimada, N Alfulaij, LA Seale - International journal of molecular …, 2021 - mdpi.com
Selenium (Se) is an essential trace element that is necessary for various metabolic
processes, including protection against oxidative stress, and proper cardiovascular function …

[HTML][HTML] Cardiovascular mortality attributable to dietary risk factors in 51 countries in the WHO European Region from 1990 to 2016: a systematic analysis of the Global …

T Meier, K Gräfe, F Senn, P Sur, GI Stangl… - European journal of …, 2019 - Springer
This study was performed to highlight the relationship between single dietary risk factors and
cardiovascular diseases (CVDs) in the WHO European Region. We used the comparative …

The importance of selenium and zinc deficiency in cardiovascular disorders

P Gać, K Czerwińska, P Macek, A Jaremków… - Environmental …, 2021 - Elsevier
Cardiovascular diseases often linked with lifestyle are among the main causes of death,
especially in the elderly population. The role of trace elements in health and disease has …

[HTML][HTML] Selenium and RNA virus interactions: potential implications for SARS-CoV-2 infection (COVID-19)

L Hiffler, B Rakotoambinina - Frontiers in Nutrition, 2020 - frontiersin.org
SARS-CoV-2 is an RNA virus responsible for the COVID-19 pandemic that already claimed
more than 340,000 lives worldwide as of May 23, 2020, the majority of which are elderly …

Mitochondrial dysfunction and mitochondrial therapies in heart failure

C Wu, Z Zhang, W Zhang, X Liu - Pharmacological Research, 2022 - Elsevier
Cardiovascular diseases remain the leading cause of death worldwide in the last decade,
accompanied by immense health and economic burdens. Heart failure (HF), as the terminal …

Selenium status and its antioxidant role in metabolic diseases

J Huang, L Xie, A Song, C Zhang - Oxidative Medicine and …, 2022 - Wiley Online Library
Selenium (Se), in the form of selenoproteins, is an essential micronutrient that plays an
important role in human health and disease. To date, there are at least 25 selenoproteins in …

[HTML][HTML] Coenzyme Q10 supplementation–In ageing and disease

J Aaseth, J Alexander, U Alehagen - Mechanisms of Ageing and …, 2021 - Elsevier
Abstract Coenzyme Q 10 (CoQ 10) is an essential component of the mitochondrial electron
transport chain. It is also an antioxidant in cellular membranes and lipoproteins. All cells …

[HTML][HTML] Selenium, a micronutrient that modulates cardiovascular health via redox enzymology

DE Handy, J Joseph, J Loscalzo - Nutrients, 2021 - mdpi.com
Selenium (Se) is a trace nutrient that promotes human health through its incorporation into
selenoproteins in the form of the redox-active amino acid selenocysteine (Sec). There are 25 …