Actin cytoskeleton dynamics depend on a tight regulation of actin filament formation from an
intracellular pool of monomers, followed by their linkage to each other or to cell membranes …

Coronins are a conserved family of actin cytoskeleton regulators that promote cell motility
and modulate other actin-dependent processes. Although these proteins have been known …

All things flow and change… even in the stillest matter there is unseen flux and movement.
Attributed to Heraclitus (530–470 BC) From The Story of Philosophy by Will Durant …

Parasites causing malaria need to migrate in order to penetrate tissue barriers and enter
host cells. Here we show that the actin filament-binding protein coronin regulates gliding …

Arf GTPases are key regulators of both retrograde and anterograde traffic at the Golgi
complex. The Golgi-localized Arf activators, Arf-GEFs (guanine exchange factor) of the …

Phosphoinositides (PtdInsPs) modulate a plethora of functions including signal transduction
and membrane trafficking. PtdInsPs are thought to consist of seven interconvertible species …

In order for the cell to function well within a multicellular system, the mechanical properties of
the plasma membrane need to meet two different requirements: cell shape maintenance and …

An increasing number of studies have demonstrated the significant roles of the interplay
between microenvironmental mechanics in tissues and biochemical-genetic activities in …

Introduction The proteins that decipher nucleic acid-and protein-based information are well
known, however, those that read membrane-encoded information remain understudied …

Coronins are involved in the regulation of actin dynamics in a multifaceted way, participating
in cell migration and vesicular trafficking. Apicomplexan parasites, which exhibit an actin …