The role of inflammation and the gut microbiome in depression and anxiety
JM Peirce, K Alviña - Journal of neuroscience research, 2019 - Wiley Online Library
The study of the gut microbiome has increasingly revealed an important role in modulating
brain function and mental health. In this review, we underscore specific pathways and …
brain function and mental health. In this review, we underscore specific pathways and …
From stress to inflammation and major depressive disorder: a social signal transduction theory of depression.
GM Slavich, MR Irwin - Psychological bulletin, 2014 - psycnet.apa.org
Major life stressors, especially those involving interpersonal stress and social rejection, are
among the strongest proximal risk factors for depression. In this review, we propose a …
among the strongest proximal risk factors for depression. In this review, we propose a …
Effect of anti-inflammatory treatment on depression, depressive symptoms, and adverse effects: a systematic review and meta-analysis of randomized clinical trials
O Köhler, ME Benros, M Nordentoft, ME Farkouh… - JAMA …, 2014 - jamanetwork.com
Importance Several studies have reported antidepressant effects of anti-inflammatory
treatment; however, the results have been conflicting and detrimental adverse effects may …
treatment; however, the results have been conflicting and detrimental adverse effects may …
Inflammation in depression and the potential for anti-inflammatory treatment
O Kohler, J Krogh, O Mors… - Current …, 2016 - ingentaconnect.com
Accumulating evidence supports an association between depression and inflammatory
processes, a connection that seems to be bidirectional. Clinical trials have indicated …
processes, a connection that seems to be bidirectional. Clinical trials have indicated …
Inflammation and depression: a causal or coincidental link to the pathophysiology?
BE Leonard - Acta neuropsychiatrica, 2018 - cambridge.org
This review summarises the evidence that chronic low grade inflammation triggers changes
that contribute to the mental and physical ill health of patients with major depression …
that contribute to the mental and physical ill health of patients with major depression …
Clarifying the role of sleep in depression: a narrative review
SR Pandi-Perumal, JM Monti, D Burman… - Psychiatry …, 2020 - Elsevier
It has been established that 4.4 to 20% of the general population suffers from a major
depressive disorder (MDD), which is frequently associated with a dysregulation of normal …
depressive disorder (MDD), which is frequently associated with a dysregulation of normal …
Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications
JC Felger, FE Lotrich - Neuroscience, 2013 - Elsevier
Mounting evidence indicates that inflammatory cytokines contribute to the development of
depression in both medically ill and medically healthy individuals. Cytokines are important …
depression in both medically ill and medically healthy individuals. Cytokines are important …
Reductions in anti-inflammatory gut bacteria are associated with depression in a sample of young adults
We assessed the gut microbiota of 90 American young adults, comparing 43 participants
with major depressive disorder (MDD) and 47 healthy controls, and found that the MDD …
with major depressive disorder (MDD) and 47 healthy controls, and found that the MDD …
The link between multiple sclerosis and depression
A Feinstein, S Magalhaes, JF Richard, B Audet… - Nature Reviews …, 2014 - nature.com
Depression—be it a formal diagnosis based on consensus clinical criteria, or a collection of
symptoms revealed by a self-report rating scale—is common in patients with multiple …
symptoms revealed by a self-report rating scale—is common in patients with multiple …
Inflamed moods: a review of the interactions between inflammation and mood disorders
Mood disorders have been recognized by the World Health Organization (WHO) as the
leading cause of disability worldwide. Notwithstanding the established efficacy of …
leading cause of disability worldwide. Notwithstanding the established efficacy of …