Tramadol hydrochloride: pharmacokinetics, pharmacodynamics, adverse side effects, co-administration of drugs and new drug delivery systems

M Vazzana, T Andreani, J Fangueiro, C Faggio… - Biomedicine & …, 2015 - Elsevier
Tramadol hydrochloride (TrHC) is a synthetic analgesic drug exhibiting opioid and non-
opioid properties, acting mainly on the central nervous system. It has been mostly used to …

Electrochemical kinetics and detection of paracetamol by stevensite-modified carbon paste electrode in biological fluids and pharmaceutical formulations

M Gharous, L Bounab, FJ Pereira, M Choukairi… - International Journal of …, 2023 - mdpi.com
Paracetamol (PCT), or acetaminophen, is an important drug used worldwide for various
clinical purposes. However, the excessive or indiscriminate use of PCT can provoke liver …

Development and validation of an RP-HPLC-PDA method for determination of paracetamol, caffeine and tramadol hydrochloride in pharmaceutical formulations

FJ Pereira, A Rodríguez-Cordero, R López, LC Robles… - Pharmaceuticals, 2021 - mdpi.com
Paracetamol (acetaminophen)(PAR), caffeine (CAF) and tramadol hydrochloride (TRA) are
important drugs widely used for many clinical purposes. Determination of their contents is of …

Novel self-assembly Pd (II)-schiff base complex modified glassy carbon electrode for electrochemical detection of paracetamol

MA Hefnawy, SS Medany, SA Fadlallah, RM El-Sherif… - Electrocatalysis, 2022 - Springer
A self-assembly Pd-Schiff base complex was synthesized and used as an electrochemical
sensor in phosphate buffer solution, where it enhanced the electrocatalytic activity toward …

CuONPs/MWCNTs/carbon paste modified electrode for determination of tramadol: theoretical and experimental investigation

R Razavi, M Amiri, K Divsalar, A Foroumadi - Scientific Reports, 2023 - nature.com
A practical technique was applied to fabricate CuO nanostructures for use as the
electrocatalyst. The green synthesis of cupric oxide nanoparticles (CuO NPs) via co …

Comprehensive Overview of Analytical and Bioanalytical Methodologies for the Opioid analgesics-Tramadol and Combinations

K Adila, S Kathirvel - Analytical Biochemistry, 2024 - Elsevier
Synthetic opioids like Tramadol are used to treat mild to moderate pain. Its ability to relieve
pain is about a tenth that of morphine. Furthermore, Tramadol shares similar effects on …

[HTML][HTML] Quantification of theophylline or paracetamol in milk matrices by high-performance liquid chromatography

TAP Fernandes, JP Aguiar, AI Fernandes… - Journal of pharmaceutical …, 2017 - Elsevier
A simple, accurate and sensitive high-performance liquid chromatography (HPLC) method
was developed, validated and applied to the determination of either theophylline or …

Stability-indicating RP-HPLC method for simultaneous quantitation of tramadol and aceclofenac in presence of their major degradation products: Method development …

M Gousuddin, P Sengupta, B Chatterjee… - Journal of Liquid …, 2017 - Taylor & Francis
Primary objective of this study was to develop a stability-indicating reverse-phase high-
performance liquid chromatography (HPLC) method for simultaneous quantitation of …

[PDF][PDF] A stability indicating method for the simultaneous estimation of acetaminophen and tramadol in pharmaceutical dosage form

F Batool, O Ahmed, A Rasheed - American Journal of PharmTech …, 2015 - researchgate.net
ABSTRACT A sensitive and selective RP-HPLC method is described for the determination of
stability in Acetaminophen and Tramadol dosage forms. Chromatographic separation was …

Development of a new voltammetric method for aceclofenac determination on glassy carbon electrode modified with hierarchical nanocomposite

A Górska, B Paczosa-Bator, J Gaidukevič, R Piech - Sensors, 2022 - mdpi.com
Aceclofenac (ACL) is an anti-inflammatory drug, which is taken by patients who mainly suffer
from rheumatoid conditions. In this work, we propose a new voltammetric method that allows …