The history of brain drug delivery is reviewed beginning with the first demonstration, in 1914,
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …

The main limitation to the success of central nervous system (CNS) therapies lies in the
difficulty for drugs to cross the blood–brain barrier (BBB) and reach the brain. Regarding its …

CNS tumors remain among the deadliest forms of cancer, resisting conventional and new
treatment approaches, with mortality rates staying practically unchanged over the past 30 …

Recent advances in maximum safe glioma resection have included the introduction of a host
of visualization techniques to complement intraoperative white-light imaging of tumors …

Simple Summary Glioblastoma (GBM) is a common primary brain tumor with a short median
overall survival despite aggressive treatment with resection, chemotherapy, and radiation …

This review focuses on the architecture and functions of theranostic nanoparticles. In the
beginning, this review highlights the importance of diagnostic imaging with a brief …

Initially thought to be useful only to reach tissues in the immediate vicinity of the CSF
circulatory system, CSF circulation is now increasingly viewed as a viable pathway to deliver …

Even though the last decade has seen a surge in the identification of molecular targets and
targeted therapies in pediatric brain tumors, the blood brain barrier (BBB) remains a …

Brain research is a cutting-edge topic but it remains challenging to achieve noninvasive
sensitive diagnosis of brain diseases. Lanthanide nanocrystals (NCs) with near-infrared II …

Drug delivery by nano-drug carriers in magnetic drug targeting has shown a promising
future in various cancer tumor treatments. The distinguishing properties of nanocarriers …