The immunology of multiple sclerosis
KE Attfield, LT Jensen, M Kaufmann… - Nature Reviews …, 2022 - nature.com
Our incomplete understanding of the causes and pathways involved in the onset and
progression of multiple sclerosis (MS) limits our ability to effectively treat this complex …
progression of multiple sclerosis (MS) limits our ability to effectively treat this complex …
Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis
MA Friese, B Schattling, L Fugger - Nature Reviews Neurology, 2014 - nature.com
Multiple sclerosis (MS) is the most frequent chronic inflammatory disease of the CNS, and
imposes major burdens on young lives. Great progress has been made in understanding …
imposes major burdens on young lives. Great progress has been made in understanding …
Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data
Single-cell RNA sequencing (scRNA-seq) provides unique insights into the pathology and
cellular origin of disease. We introduce single-cell disease relevance score (scDRS), an …
cellular origin of disease. We introduce single-cell disease relevance score (scDRS), an …
Locus for severity implicates CNS resilience in progression of multiple sclerosis
MultipleMS Consortium Harroud Adil 1 78 78 Jónsdóttir … - Nature, 2023 - nature.com
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that
results in significant neurodegeneration in the majority of those affected and is a common …
results in significant neurodegeneration in the majority of those affected and is a common …
[HTML][HTML] Changes in gut microbiota and multiple sclerosis: a systematic review
A Ordoñez-Rodriguez, P Roman… - International Journal of …, 2023 - mdpi.com
Introduction: Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease
mediated by autoimmune reactions against myelin proteins and gangliosides in the grey …
mediated by autoimmune reactions against myelin proteins and gangliosides in the grey …
The genetics of multiple sclerosis: an up‐to‐date review
Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system
that often leads to disability in young adults. Treatment options are limited and often only …
that often leads to disability in young adults. Treatment options are limited and often only …
Genetics of multiple sclerosis: an overview and new directions
NA Patsopoulos - Cold Spring Harbor …, 2018 - perspectivesinmedicine.cshlp.org
The contribution of genetic inheritance in multiple sclerosis was established early on.
Although multiple sclerosis is not a Mendelian disease, its incidence and prevalence is …
Although multiple sclerosis is not a Mendelian disease, its incidence and prevalence is …
Disability in multiple sclerosis: a reference for patients and clinicians
Objective: To create a reference table of disability outcomes in multiple sclerosis (MS) that
would enable patients to rank their disability relative to others' with similar disease duration …
would enable patients to rank their disability relative to others' with similar disease duration …
[HTML][HTML] The efficacy of cannabis on multiple sclerosis-related symptoms
Multiple sclerosis (MS) is known as an autoimmune disease that damages the neurons in
the central nervous system. MS is characterized by its most common symptoms of spasticity …
the central nervous system. MS is characterized by its most common symptoms of spasticity …
Age related multiple sclerosis severity score: disability ranked by age
A Manouchehrinia, H Westerlind… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Background: The Multiple Sclerosis Severity Score (MSSS) is obtained by normalising the
Expanded Disability Status Scale (EDSS) score for disease duration and has been a …
Expanded Disability Status Scale (EDSS) score for disease duration and has been a …