A fundamental goal in cancer research is to understand the mechanisms of cell
transformation. This is key to developing more efficient cancer detection methods and …

Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs
and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an …

In recent decades, with the continuous development of high‐throughput sequencing
technology, data volume in medical research has increased, at the same time, almost all …

Gliomas are the most common and malignant intracranial tumors in adults. Recent studies
have revealed the significance of functional genomics for glioma pathophysiological studies …

Multi-omics, variously called integrated omics, pan-omics, and trans-omics, aims to combine
two or more omics data sets to aid in data analysis, visualization and interpretation to …

Proteomics has become an important field in molecular sciences, as it provides valuable
information on the identity, expression levels, and modification of proteins. For example …

Metastatic cancer is a major cause of death and is associated with poor treatment efficacy. A
better understanding of the characteristics of late-stage cancer is required to help adapt …

Gene expression profiling is nowadays routinely performed on clinically relevant samples
(eg, from tumor specimens). Such measurements are often obtained from bulk samples …

To the Editor—The International Cancer Genome Consortium (ICGC) is a global initiative to
build a comprehensive catalog of mutational abnormalities in the major tumor types. Here …

Widespread clinical laboratory implementation of next-generation sequencing–based
cancer testing has highlighted the importance and potential benefits of standardizing the …