Direct and indirect impacts of synthetic biology on biodiversity conservation

NBW Macfarlane, J Adams, EL Bennett, TM Brooks… - Iscience, 2022 - cell.com
The world's biodiversity is in crisis. Synthetic biology has the potential to transform
biodiversity conservation, both directly and indirectly, in ways that are negative and positive …

The promise and challenge of genetic biocontrol approaches for malaria elimination

S James, M Santos - Tropical Medicine and Infectious Disease, 2023 - mdpi.com
Malaria remains an ongoing public health challenge, with over 600,000 deaths in 2021, of
which approximately 96% occurred in Africa. Despite concerted efforts, the goal of global …

Small-scale release of non-gene drive mosquitoes in Burkina Faso: from engagement implementation to assessment, a learning journey

L Pare Toe, N Barry, AD Ky, S Kekele, W Meda… - Malaria journal, 2021 - Springer
Background Innovative tools are needed to complement the existing approach for malaria
elimination. Gene drive mosquitoes are one potential new technology in the control of …

Articulating ethical principles guiding Target Malaria's engagement strategy

AJ Roberts, D Thizy - Malaria Journal, 2022 - Springer
Progress in gene drive research has engendered a lively discussion about community
engagement and the ethical standards the work hinges on. While there is broad agreement …

Operationalizing stakeholder engagement for gene drive research in malaria elimination in Africa—translating guidance into practice

L Pare Toe, B Dicko, R Linga, N Barry, M Drabo… - Malaria Journal, 2022 - Springer
Gene drive mosquitoes are increasingly considered a potential transformational tool for
vector control of malaria mosquitoes. As part of efforts to promote responsible research in …

From the lab to the last mile: Deploying transgenic approaches against mosquitoes

RJ St. Leger - Frontiers in Tropical Diseases, 2021 - frontiersin.org
Ingenious exploitation of transgenic approaches to produce malaria resistant or sterile
mosquitoes, or hypervirulent mosquito pathogens, has produced many potential solutions to …

Lessons learned from the introduction of genetically engineered crops: relevance to gene drive deployment in Africa

H Quemada - Transgenic Research, 2022 - Springer
The application of gene drives to achieve public health goals, such as the suppression of
Anopheles gambiae populations, or altering their ability to sustain Plasmodium spp …

Assessing CRISPR/Cas9 potential in SDG3 attainment: malaria elimination—regulatory and community engagement landscape

A Snuzik - Malaria Journal, 2024 - Springer
Elimination of malaria has become a United Nations member states target: Target 3.3 of the
sustainable development goal no. 3 (SDG3). Despite the measures taken, the attainment of …

[HTML][HTML] Taking stock: Is gene drive research delivering on its principles?

AJ Roberts, K Hackett, I Coche… - Gates Open …, 2024 - gatesopenresearch.org
Gene drive technology has been recognized for its potential to provide durable and cost-
effective solutions for previously intractable problems in public health, conservation, and …

[图书][B] As Gods: A Moral History of the Genetic Age

M Cobb - 2022 - books.google.com
The thrilling and terrifying history of genetic engineering In 2018, scientists manipulated the
DNA of human babies for the first time. As biologist and historian Matthew Cobb shows in As …