Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond

L Luzhna, P Kathiria, O Kovalchuk - Frontiers in genetics, 2013 - frontiersin.org
Micronuclei (MN) are extra-nuclear bodies that contain damaged chromosome fragments
and/or whole chromosomes that were not incorporated into the nucleus after cell division …

Factors affecting the incidence of genotoxicity biomarkers in peripheral blood lymphocytes: impact on design of biomonitoring studies

JM Battershill, K Burnett, S Bull - Mutagenesis, 2008 - academic.oup.com
A review of risk factors affecting background rates of micronuclei and chromosomal
aberration (CA) formation in peripheral blood lymphocytes (PBLs) was undertaken with a …

Micronucleus frequency in human umbilical cord lymphocytes

M Levario-Carrillo, M Sordo, F Rocha… - … /Genetic Toxicology and …, 2005 - Elsevier
The human fetus is exposed to a variety of environmental agents and drugs which cross the
placenta and can induce DNA damage. Micronucleus (MN) determination is a suitable and …

An automated scoring procedure for the micronucleus test by image analysis

D Varga, T Johannes, S Jainta, S Schuster… - …, 2004 - academic.oup.com
The micronucleus assay (MNT) in human lymphocytes is frequently used to assess
chromosomal damage as a consequence of environmental mutagen exposure, to assess …

Micronuclei in neonates and children: effects of environmental, genetic, demographic and disease variables

N Holland, A Fucic, DF Merlo, R Sram… - …, 2011 - academic.oup.com
Children may be more susceptible to the effects of the environmental exposure and medical
treatments than adults; however, limited information is available about the differences in …

Metal toxicity assessment by sentinel species of mangroves: In situ case study integrating chemical and biomarkers analyses

LF de Almeida Duarte, CA de Souza… - Ecotoxicology and …, 2017 - Elsevier
Globally, there is a lack of knowledge about tropical ecotoxicology dealing with the potential
impact of metal contamination in mangrove ecosystem. This habitat is considered a nursery …

Multi-level biological responses in Ucides cordatus (Linnaeus, 1763)(Brachyura, Ucididae) as indicators of conservation status in mangrove areas from the western …

LF de Almeida Duarte, CA de Souza, CR Nobre… - Ecotoxicology and …, 2016 - Elsevier
There is a global lack of knowledge on tropical ecotoxicology, particularly in terms of
mangrove areas. These areas often serve as nurseries or homes for several animal species …

Genome-health nutrigenomics and nutrigenetics: nutritional requirements or 'nutriomes' for chromosomal stability and telomere maintenance at the individual level …

C Bull, M Fenech - Proceedings of the Nutrition Society, 2008 - cambridge.org
It is becoming increasingly evident that (a) risk for developmental and degenerative disease
increases with more DNA damage, which in turn is dependent on nutritional status, and (b) …

Children's exposure to environmental pollutants and biomarkers of genetic damage: I. Overview and critical issues

M Neri, S Bonassi, LE Knudsen, RJ Sram… - … Research/Reviews in …, 2006 - Elsevier
In the last decade, molecular epidemiological studies have provided new perspectives on
studying environmental risks in pediatric populations, based on the growing understanding …

Cytogenetic biomonitoring in patients exposed to dental X-rays: comparison between adults and children

DA Ribeiro, G De Oliveira… - Dentomaxillofacial …, 2008 - academic.oup.com
Objectives: The aim of the present study was to comparatively evaluate the DNA damage
(micronucleus) and cellular death (pyknosis, karyolysis and karyorrhexis) of exfoliated …