[HTML][HTML] Diabetic neuropathic pain: physiopathology and treatment
AK Schreiber, CFM Nones, RC Reis… - World journal of …, 2015 - ncbi.nlm.nih.gov
Diabetic neuropathy is a common complication of both type 1 and type 2 diabetes, which
affects over 90% of the diabetic patients. Although pain is one of the main symptoms of …
affects over 90% of the diabetic patients. Although pain is one of the main symptoms of …
Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA
There is increasing interest in the use of edited proton magnetic resonance spectroscopy for
the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a …
the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a …
Gannet: A batch‐processing tool for the quantitative analysis of gamma‐aminobutyric acid–edited MR spectroscopy spectra
Purpose The purpose of this study is to describe the Gannet toolkit for the quantitative batch
analysis of gamma‐aminobutyric acid (GABA)‐edited MRS data. Materials and Methods …
analysis of gamma‐aminobutyric acid (GABA)‐edited MRS data. Materials and Methods …
[HTML][HTML] New perspective in diabetic neuropathy: from the periphery to the brain, a call for early detection, and precision medicine
H Yang, G Sloan, Y Ye, S Wang, B Duan… - Frontiers in …, 2020 - frontiersin.org
Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes
mellitus. It leads to distressing and expensive clinical sequelae such as foot ulceration, leg …
mellitus. It leads to distressing and expensive clinical sequelae such as foot ulceration, leg …
A new look at painful diabetic neuropathy
G Sloan, P Shillo, D Selvarajah, J Wu… - Diabetes research and …, 2018 - Elsevier
The prevalence of diabetes mellitus and its chronic complications continue to increase
alarmingly. Consequently, the massive expenditure on diabetic distal symmetrical …
alarmingly. Consequently, the massive expenditure on diabetic distal symmetrical …
Tissue correction for GABA‐edited MRS: Considerations of voxel composition, tissue segmentation, and tissue relaxations
Purpose To develop a tissue correction for GABA‐edited magnetic resonance spectroscopy
(MRS) that appropriately addresses differences in voxel gray matter (GM), white matter …
(MRS) that appropriately addresses differences in voxel gray matter (GM), white matter …
Big GABA: Edited MR spectroscopy at 24 research sites
M Mikkelsen, PB Barker, PK Bhattacharyya, MK Brix… - Neuroimage, 2017 - Elsevier
Magnetic resonance spectroscopy (MRS) is the only biomedical imaging method that can
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid …
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid …
Pregabalin rectifies aberrant brain chemistry, connectivity, and functional response in chronic pain patients
Background: Chronic pain remains a significant challenge for modern health care as its
pathologic mechanisms are largely unknown and preclinical animal models suffer from …
pathologic mechanisms are largely unknown and preclinical animal models suffer from …
Frontal gamma-aminobutyric acid concentrations are associated with cognitive performance in older adults
Background Gamma-aminobutyric acid (GABA), the brain's principal inhibitory
neurotransmitter, has been associated with perceptual and attentional functioning. Recent …
neurotransmitter, has been associated with perceptual and attentional functioning. Recent …
Edited 1H magnetic resonance spectroscopy in vivo: Methods and metabolites
The Proton magnetic resonance (1H‐MRS) spectrum contains information about the
concentration of tissue metabolites within a predefined region of interest (a voxel). The …
concentration of tissue metabolites within a predefined region of interest (a voxel). The …