Amyotrophic lateral sclerosis (ALS) is the most common adult onset motor neuron disease
with no effective disease modifying therapies at present. Spinal cord degeneration is a …

For the past 25 years, the field of neuroimaging has witnessed the development of several
software packages for processing multi-parametric magnetic resonance imaging (mpMRI) to …

Human brain atlases have been evolving tremendously, propelled recently by brain big
projects, and driven by sophisticated imaging techniques, advanced brain mapping …

Template-based analysis of multi-parametric MRI data of the spinal cord sets the foundation
for standardization and reproducibility, thereby helping the discovery of new biomarkers of …

Objective In multiple sclerosis (MS), cerebral gray matter (GM) atrophy correlates more
strongly than white matter (WM) atrophy with disability. The corresponding relationships in …

Template-based analysis has proven to be an efficient, objective and reproducible way of
extracting relevant information from multi-parametric MRI data. Using common atlases, it is …

The field of spinal cord MRI is lacking a common template, as existing for the brain, which
would allow extraction of multi-parametric data (diffusion-weighted, magnetization transfer …

The study of spontaneous fluctuations in the blood-oxygen-level-dependent (BOLD) signal
has recently been extended from the brain to the spinal cord. Two ultra-high field functional …

Segmenting the spinal cord contour is a necessary step for quantifying spinal cord atrophy in
various diseases. Delineating gray matter (GM) and white matter (WM) is also useful for …

Being able to finely characterize the spinal cord (SC) microstructure and its alterations is a
key point when investigating neural damage mechanisms encountered in different central …