The transcription factor nuclear factor erythroid 2 p45-related factor 2 (Nrf2) is the master
regulator of the cellular redox homeostasis. Nrf2 target genes comprise of a large network of …

Curcumin is widely consumed in Asia either as turmeric directly or as one of the culinary
ingredients in food recipes. The benefits of curcumin in different organ systems have been …

Curcumin (diferuloylmethane), a polyphenol extracted from the plant Curcuma longa, is
widely used in Southeast Asia, China and India in food preparation and for medicinal …

K elch‐like ECH‐associated protein 1 (K eap1)‐nuclear factor erythroid 2‐related factor 2 (N
rf2)‐antioxidant response elements (ARE) pathway represents one of the most important …

Oxidative stress suppresses animal health, performance, and production, subsequently
impacting economic feasibility; hence, maintaining and improving oxidative status especially …

The global popularity of herbal supplements and the promise they hold in treating various
disease states has caused an unprecedented interest in understanding the molecular basis …

Research into human biotransformation and elimination systems continues to evolve.
Various clinical and in vivo studies have been undertaken to evaluate the effects of foods …

Despite the capacity of chaperones and other homeostatic components to restore folding
equilibrium, cells appear poorly adapted for chronic oxidative stress that increases in cancer …

Type 2 diabetes mellitus (DM) has reached pandemic proportions and effective prevention
strategies are wanted. Its onset is accompanied by cellular distress, the nuclear factor …

Modulation of endogenous cellular defense mechanisms represents an innovative approach
to therapeutic intervention in diseases causing chronic tissue damage, such as in …