Cellular and physiological mechanisms underlying blood flow regulation in the retina and choroid in health and disease

J Kur, EA Newman, T Chan-Ling - Progress in retinal and eye research, 2012 - Elsevier
We review the cellular and physiological mechanisms responsible for the regulation of blood
flow in the retina and choroid in health and disease. Due to the intrinsic light sensitivity of the …

The impact of ocular blood flow in glaucoma

J Flammer, S Orgül, VP Costa, N Orzalesi… - Progress in retinal and …, 2002 - Elsevier
Two principal theories for the pathogenesis of glaucomatous optic neuropathy (GON) have
been described—a mechanical and a vascular theory. Both have been defended by various …

Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal …

N Patton, T Aslam, T MacGillivray, A Pattie… - Journal of …, 2005 - Wiley Online Library
The retinal and cerebral microvasculatures share many morphological and physiological
properties. Assessment of the cerebral microvasculature requires highly specialized and …

Retinal image analysis: concepts, applications and potential

N Patton, TM Aslam, T MacGillivray, IJ Deary… - Progress in retinal and …, 2006 - Elsevier
As digital imaging and computing power increasingly develop, so too does the potential to
use these technologies in ophthalmology. Image processing, analysis and computer vision …

The complex interaction between ocular perfusion pressure and ocular blood flow–relevance for glaucoma

D Schmidl, G Garhofer, L Schmetterer - Experimental eye research, 2011 - Elsevier
Glaucoma is an optic neuropathy of unknown origin. The most important risk factor for the
disease is an increased intraocular pressure (IOP). Reducing IOP is associated with …

Nitric oxide regulates retinal vascular tone in humans

GT Dorner, G Garhofer, B Kiss… - American Journal …, 2003 - journals.physiology.org
The purpose of the present study was to investigate the contribution of basal nitric oxide
(NO) on retinal vascular tone in humans. In addition, we set out to elucidate the role of NO in …

Use of the retinal vessel analyzer in ocular blood flow research

G Garhofer, T Bek, AG Boehm, D Gherghel… - Acta …, 2010 - Wiley Online Library
Acta Ophthalmol. 2010: 88: 717–722 Abstract. The present article describes a standard
instrument for the continuous online determination of retinal vessel diameters, the …

Role of nitric oxide in the control of ocular blood flow

L Schmetterer, K Polak - Progress in retinal and eye research, 2001 - Elsevier
In the recent years it has been recognized that nitric oxide is an important regulator of ocular
blood flow. Nitric oxide is involved in the control of basal blood flow in the choroid, optic …

Reduced response of retinal vessel diameters to flicker stimulation in patients with diabetes

G Garhöfer, C Zawinka, H Resch, P Kothy… - British Journal of …, 2004 - bjo.bmj.com
Background/aim: Stimulation of the retina with flickering light increases retinal arterial and
venous diameters in animals and humans, indicating a tight coupling between neural activity …

Influence of flickering light on the retinal vessels in diabetic patients

A Mandecka, J Dawczynski, M Blum, N Muller… - Diabetes …, 2007 - Am Diabetes Assoc
OBJECTIVE—Stimulation of the retina with flickering light increases retinal vessel diameters
in humans. Nitric oxide is a mediator of the retinal vasodilation to flicker. The reduction of …