Rhodococcus equi is the only recognized animal pathogenic species within an extended
genus of metabolically versatile Actinobacteria of considerable biotechnological interest …

Simple Summary Pneumonia caused by soil bacteria Rhodococcus equi occurs in the foals
of most horse breeds all over the world, posing a significant challenge for veterinary …

The virulence-associated protein A (VapA) produced by virulent Rhodococcus equi allows it
to replicate in macrophages and cause pneumonia in foals. It is unknown how VapA …

Professional phagocytic cells such as macrophages are a central part of innate immune
defence. They ingest microorganisms into membrane‐bound compartments (phagosomes) …

Pathogenic Rhodococcus equi release the virulence‐associated protein A (VapA) within
macrophage phagosomes. VapA permeabilizes phagosome and lysosome membranes and …

Rhodococcus equi is a Gram‐positive facultative intracellular pathogen associated with life‐
threatening bronchopneumonial disease in foals. Key to R. equi's intracellular survival in …

Abstract Gram‐positive Rhodococcus equi (Prescotella equi) is a lung pathogen of foals and
immunocompromised humans. Intra‐macrophage multiplication requires production of the …

The voltage-gated Na+ channel β1 subunit, encoded by SCN1B, regulates cell surface
expression and gating of α subunits and participates in cell adhesion. β1 is cleaved by α/β …

Rhodococcus equi is a multihost, facultative intracellular bacterial pathogen that primarily
causes pneumonia in foals less than six months in age and immunocompromised people …

Rhodococcus equi is a facultative intracellular bacterium that can escape from bactericidal
mechanisms associated with phagocytosis. Virulence-associated protein A (VapA), encoded …