Inflammatory bowel disease (IBD) is a complex multifactorial disease of unknown etiology.
Thus, dozens of different animal models of IBD have been developed in past decades …

Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

A key challenge for the effective treatment of gastrointestinal diseases including
inflammatory bowel disease is to develop an orally administered drug delivery system …

Aims Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) caused by
multiple factors. Studies have shown that epithelial cell damage was associated with …

Background & aims Inflammatory bowel disease (IBD) is characterised by chronic intestinal
inflammation, resulting from dysregulation of the mucosal immune system and compromised …

The most widely used and characterized experimental model of ulcerative colitis (UC) is the
epithelial erosion, dextran sulfate sodium (DSS)‐induced colitis, which is developed by …

Leucine-rich repeat kinase 2 (LRRK2) has been identified by genome-wide association
studies as being encoded by a major susceptibility gene for Crohn's disease. Here we found …

Ulcerative colitis is a common chronic inflammatory disease of the colon and rectum,
resulting from a dysregulated immune response towards intraluminal antigens in a …

Ulcerative colitis is a nonspecific inflammatory disorder characterized by oxidative and
nitrosative stress, leucocyte infiltration and upregulation of inflammatory mediators …

Inflammatory bowel disease lacks a long-lasting and broadly effective therapy. Here, by
taking advantage of the anti-infection and anti-inflammatory properties of natural antibodies …