[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

A review of toxicity and mechanisms of individual and mixtures of heavy metals in the environment

X Wu, SJ Cobbina, G Mao, H Xu, Z Zhang… - … Science and Pollution …, 2016 - Springer
The rational for the study was to review the literature on the toxicity and corresponding
mechanisms associated with lead (Pb), mercury (Hg), cadmium (Cd), and arsenic (As) …

Environmental heavy metals and cardiovascular diseases: Status and future direction

AM Yang, K Lo, TZ Zheng, JL Yang, YN Bai… - Chronic diseases and …, 2020 - mednexus.org
Cardiovascular disease (CVD) and environmental degradation are leading global health
problems of our time. Recent studies have linked exposure to heavy metals to the risks of …

Heavy metal exposure and metabolic syndrome: evidence from human and model system studies

A Planchart, A Green, C Hoyo, CJ Mattingly - Current environmental health …, 2018 - Springer
Abstract Purpose of Review Metabolic syndrome (MS) describes the co-occurrence of
conditions that increase one's risk for heart disease and other disorders such as diabetes …

Chronic exposure to low concentrations of lead induces metabolic disorder and dysbiosis of the gut microbiota in mice

J Xia, C Jin, Z Pan, L Sun, Z Fu, Y Jin - Science of the Total Environment, 2018 - Elsevier
Lead (Pb) is one of the most prevalent toxic, nonessential heavy metals that can
contaminate food and water. In this study, effects of chronic exposure to low concentrations …

Epigenetics, obesity and early-life cadmium or lead exposure

SS Park, DA Skaar, RL Jirtle, C Hoyo - Epigenomics, 2017 - Taylor & Francis
Obesity is a complex and multifactorial disease, which likely comprises multiple subtypes.
Emerging data have linked chemical exposures to obesity. As organismal response to …

Perinatal lead exposure alters gut microbiota composition and results in sex-specific bodyweight increases in adult mice

J Wu, XW Wen, C Faulk, K Boehnke… - Toxicological …, 2016 - academic.oup.com
Heavy metal pollution is a principle source of environmental contamination. Epidemiological
and animal data suggest that early life lead (Pb) exposure results in critical effects on …

Obesogen effects after perinatal exposure of 4, 4′-sulfonyldiphenol (Bisphenol S) in C57BL/6 mice

LI Del Moral, L Le Corre, H Poirier, I Niot, T Truntzer… - Toxicology, 2016 - Elsevier
Bisphenol A were removed from consumer products and replaced by chemical substitutes
such as Bisphenol S (BPS). Based on their structural similarity, BPS may be obesogen like …

Health repercussions of environmental exposure to lead: Methylation perspective

SS Shiek, MS Mani, SP Kabekkodu, HS Dsouza - Toxicology, 2021 - Elsevier
Lead (Pb) exposure has been a major public health concern for a long time now due to its
permanent adverse effects on the human body. The process of lead toxicity has still not been …

Maternal blood cadmium, lead and arsenic levels, nutrient combinations, and offspring birthweight

Y Luo, LE McCullough, JY Tzeng, T Darrah… - BMC Public Health, 2017 - Springer
Abstract Background Cadmium (Cd), lead (Pb) and arsenic (As) are common environmental
contaminants that have been associated with lower birthweight. Although some essential …