Increased expression of NK cell markers on T lymphocytes in aging and chronic activation of the immune system reflects the accumulation of effector/senescent T cells
R Tarazona, O DelaRosa, C Alonso, B Ostos… - Mechanisms of ageing …, 2001 - Elsevier
In humans, CD56, CD161, CD16, CD94 or CD57 represent prototypic markers of NK cells,
although they are also found on a subset of CD8+ T cells. We propose here that the …
although they are also found on a subset of CD8+ T cells. We propose here that the …
Human influenza viruses and CD8+ T cell responses
EJ Grant, SM Quiñones-Parra, EB Clemens… - Current opinion in …, 2016 - Elsevier
Highlights•Memory influenza-specific CD8+ T cells drive rapid recovery from influenza
disease.•CD8+ T cell memory pools cross-react with distinct influenza strains.•Universal T …
disease.•CD8+ T cell memory pools cross-react with distinct influenza strains.•Universal T …
EBV-specific CD8+ T cell memory: relationships between epitope specificity, cell phenotype, and immediate effector function
AD Hislop, NH Gudgeon, MFC Callan… - The Journal of …, 2001 - journals.aai.org
EBV infection in humans induces CD8+ T cell memory to viral epitopes derived from both
lytic and latent cycle Ags. We have analyzed the relationship between the phenotype and …
lytic and latent cycle Ags. We have analyzed the relationship between the phenotype and …
Chronic immune activation associated with chronic helminthic and human immunodeficiency virus infections: role of hyporesponsiveness and anergy
G Borkow, Z Bentwich - Clinical Microbiology Reviews, 2004 - Am Soc Microbiol
Chronic immune activation is one of the hallmarks of human immunodeficiency virus (HIV)
infection. It is present also, with very similar characteristics, in very large human populations …
infection. It is present also, with very similar characteristics, in very large human populations …
Loss of CD28 expression on CD8+ T cells is induced by IL-2 receptor γ chain signalling cytokines and type I IFN, and increases susceptibility to activation-induced …
NJ Borthwick, M Lowdell, M Salmon… - International …, 2000 - academic.oup.com
Abstract CD8+ CD28–T cells are selectively expanded during viral infections, indicating their
importance in anti-viral immune responses. Since little is known about the differentiation of …
importance in anti-viral immune responses. Since little is known about the differentiation of …
Weak anti-HIV CD8+ T-cell effector activity in HIV primary infection
M Dalod, M Dupuis, JC Deschemin… - The Journal of …, 1999 - Am Soc Clin Investig
HIV-specific CD8+ T cells play a major role in the control of virus during HIV primary
infection (PI) but do not completely prevent viral replication. We used IFN-γ enzyme-linked …
infection (PI) but do not completely prevent viral replication. We used IFN-γ enzyme-linked …
Broad, Intense Anti-Human Immunodeficiency Virus (HIV) Ex Vivo CD8+ Responses in HIV Type 1-Infected Patients: Comparison with Anti-Epstein-Barr Virus …
M Dalod, M Dupuis, JC Deschemin, D Sicard… - Journal of …, 1999 - Am Soc Microbiol
The ex vivo antiviral CD8+ repertoires of 34 human immunodeficiency virus (HIV)-
seropositive patients with various CD4+ T-cell counts and virus loads were analyzed by …
seropositive patients with various CD4+ T-cell counts and virus loads were analyzed by …
Human cytotoxic T lymphocyte responses to live attenuated 17D yellow fever vaccine: identification of HLA-B35-restricted CTL epitopes on nonstructural proteins NS1 …
MDT Co, M Terajima, J Cruz, FA Ennis, AL Rothman - Virology, 2002 - Elsevier
Yellow fever virus (YFV) is a reemerging problem despite the existence of an effective live-
attenuated vaccine. The induction of YFV-neutralizing antibodies undoubtedly contributes to …
attenuated vaccine. The induction of YFV-neutralizing antibodies undoubtedly contributes to …
Significance of senescence for virus-specific memory T cell responses: rapid ageing during chronic stimulation of the immune system
There is a generalized age-related decline in immune responses which leads to increased
susceptibility of elderly to infection and, possibly, to autoimmune disease and cancer. This is …
susceptibility of elderly to infection and, possibly, to autoimmune disease and cancer. This is …
The double life of NK receptors: stimulation or co-stimulation?
MR Snyder, CM Weyand, JJ Goronzy - Trends in immunology, 2004 - cell.com
Stimulatory killer immunoglobulin-like receptors, NKG2D and stimulatory receptors of the
CD94–NKG2 family have duplicity in function. On natural killer (NK) cells, these receptors …
CD94–NKG2 family have duplicity in function. On natural killer (NK) cells, these receptors …