Sarcopenia: imaging assessment and clinical application

V Chianca, D Albano, C Messina, S Gitto, G Ruffo… - Abdominal …, 2022 - Springer
Sarcopenia is a progressive, generalized skeletal muscle disorder characterized by
reduction of muscle mass and strength. It is associated with increased adverse outcomes …

MRI correlates of motoneuron loss in SMA

A Sprenger-Svačina, J Haensch, K Weiss… - Journal of …, 2023 - Springer
Background Magnetic resonance imaging (MRI) is currently explored as supplemental tool
to monitor disease progression and treatment response in various neuromuscular disorders …

Fast open-source toolkit for water T2 mapping in the presence of fat from multi-echo spin-echo acquisitions for muscle MRI

F Santini, X Deligianni, M Paoletti, F Solazzo… - Frontiers in …, 2021 - frontiersin.org
Imaging has become a valuable tool in the assessment of neuromuscular diseases, and,
specifically, quantitative MR imaging provides robust biomarkers for the monitoring of …

Muscle diffusion MRI reveals autophagic buildup in a mouse model for Pompe disease

M Rohm, G Russo, X Helluy, M Froeling, V Umathum… - Scientific Reports, 2023 - nature.com
Quantitative muscle MRI is increasingly important in the non-invasive evaluation of
neuromuscular disorders and their progression. Underlying histopathotological alterations …

New insights into the spread of MRS‐based water T2 values observed in highly fatty replaced muscles

H Reyngoudt, PY Baudin, PG Carlier… - Journal of Magnetic …, 2023 - Wiley Online Library
Background The reference standard for assessing water T 2 (T 2, H2O) at high fat fraction
(FF) is 1H MRS. T 2, H2O (T 2, H2O, MRS) dependence on FF (FFMRS) has recently been …

[HTML][HTML] T2 mapping with and without fat-suppression to predict treatment response to intravenous glucocorticoid therapy for thyroid-associated ophthalmopathy

L Zhai, Q Wang, P Liu, B Luo, G Yuan… - Korean Journal of …, 2022 - ncbi.nlm.nih.gov
Objective To evaluate the performance of baseline clinical characteristics and
pretherapeutic histogram parameters derived from T2 mapping of the extraocular muscles …

Beyond mean value analysis – a voxel‐based analysis of the quantitative MR biomarker water T2 in the presence of fatty infiltration in skeletal muscle tissue of …

S Schlaeger, D Weidlich, A Zoffl… - NMR in …, 2022 - Wiley Online Library
The main pathologies in the muscles of patients with neuromuscular diseases (NMD) are
fatty infiltration and edema. Recently, quantitative magnetic resonance (MR) imaging for …

Simultaneous whole‐liver water T 1 T _1 and T 2 T _2 mapping with isotropic resolution during free‐breathing

J Stelter, K Weiss, L Steinhelfer, V Spieker… - NMR in …, 2024 - Wiley Online Library
Purpose To develop and validate a data acquisition scheme combined with a motion‐
resolved reconstruction and dictionary‐matching‐based parameter estimation to enable free …

Histogram analysis of T2 mapping for detecting early involvement of extraocular muscles in patients with thyroid-associated ophthalmopathy

P Liu, L Chen, Q Wang, B Luo, H Su, G Yuan… - Scientific Reports, 2020 - nature.com
Using histogram analysis of T2 values to detect early involvement of extraocular muscles
(EOMs) in patients with thyroid-associated ophthalmopathy (TAO). Five EOMs of each orbit …

Single‐voxel short‐TR multi‐TI multi‐TE STEAM MRS for water–fat relaxometry

S Ruschke, DC Karampinos - Magnetic Resonance in …, 2022 - Wiley Online Library
Purpose To propose a short‐TR multi‐TI multi‐TE (SHORTIE,[ˈshȯr‐tē]) STEAM single‐
voxel MRS acquisition scheme for the simultaneous assessment of T1 relaxation, T2 …