The nervous system evolved to enable navigation throughout the environment in the pursuit
of resources. Evolutionarily newer structures allowed increasingly complex adaptations but …

Neurodevelopmental disorders (NDDs) impact multiple aspects of an individual's
functioning, including social interactions, communication, and behaviors. The underlying …

Aims Accumulating evidence indicates the involvement of TRESK potassium channels in
migraine, however, effects of TRESK activation on migraine-related mechanisms remain …

BackgroundMajor psychiatric disorders (MPDs) are delineated by distinct clinical features.
However, overlapping symptoms and transdiagnostic effectiveness of medications have …

The growing interest in Kv7. 2/7.3 agonists originates from the involvement of these
channels in several brain hyperexcitability disorders. In particular, Kv7. 2/7.3 mutants have …

Potassium (K+) channels are a diverse group of ion channels which regulate the excitability
and stability of biological membranes through their effects on inward K+ flux, leading to …

Statins, widely prescribed for cholesterol management by inhibiting HMG-CoA reductase in
the cholesterol biosynthesis pathway, may also influence vertebrate development. In this …

OBJECTIVES: To evaluate for associations of polymorphisms for potassium channel genes
in patients with breast cancer who were classified as having high or low–moderate levels of …

Mammals tightly regulate their core body temperature, yet how cells sense and respond to
small temperature changes at the molecular level remains incompletely understood. Here …

Cancer remains a complex and multifaceted disease, characterized by a myriad of
molecular and cellular alterations that collectively drive tumorigenesis and progression …