Genetically encoded biosensors are the vital components of synthetic biology and metabolic
engineering, as they are regarded as powerful devices for the dynamic control of genotype …

It was already clinically apparent 150 years ago that bacterial therapy could alleviate
diseases. Recently, a burgeoning number of researchers have been using bacterial …

Microorganisms are a promising means to address many societal sustainability challenges
owing to their ability to thrive in diverse environments and interface with the microscale …

In nature, quorum sensing is one of the mechanisms bacterial populations use to
communicate with their own species or across species to coordinate behaviours. For the last …

Engineering bacteria can achieve targeted and controllable cancer therapy using synthetic
biology technology and the characteristics of tumor microenvironment. Besides, the accurate …

Oscillations are a recurrent phenomenon in biological systems across scales, but
deciphering their fundamental principles is very challenging. Here, we tackle this challenge …

Antibiotics are a key control mechanism for synthetic biology and microbiology. Resistance
genes are used to select desired cells and regulate bacterial populations, however their use …

Numerous photoreceptors and genetic circuits emerged over the past two decades and now
enable the light-dependent ie, optogenetic, regulation of gene expression in bacteria …

Optogenetics is a powerful approach that enables researchers to use light to dynamically
manipulate cellular behavior. Since the first published use of optogenetics in synthetic …

Highlights•Transcription factor-based biosensors are powerful analytical synthetic biology
tools.•Biosensors can be used for detection, metabolic engineering, and protein …