[HTML][HTML] A glycan gate controls opening of the SARS-CoV-2 spike protein
SARS-CoV-2 infection is controlled by the opening of the spike protein receptor binding
domain (RBD), which transitions from a glycan-shielded 'down'to an exposed 'up'state to …
domain (RBD), which transitions from a glycan-shielded 'down'to an exposed 'up'state to …
[HTML][HTML] A potential interaction between the SARS-CoV-2 spike protein and nicotinic acetylcholine receptors
ASF Oliveira, AA Ibarra, I Bermudez, L Casalino… - Biophysical journal, 2021 - cell.com
Changeux et al.(Changeux et al. CR Biol. 343: 33–39.) recently suggested that the SARS-
CoV-2 spike protein may interact with nicotinic acetylcholine receptors (nAChRs) and that …
CoV-2 spike protein may interact with nicotinic acetylcholine receptors (nAChRs) and that …
[HTML][HTML] Plant-produced glycosylated and in vivo deglycosylated receptor binding domain proteins of SARS-CoV-2 induce potent neutralizing responses in mice
The COVID-19 pandemic, caused by SARS-CoV-2, has rapidly spread to more than 222
countries and has put global public health at high risk. The world urgently needs cost …
countries and has put global public health at high risk. The world urgently needs cost …
Activation Pathways and Free Energy Landscapes of the SARS-CoV-2 Spike Protein
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses a spike protein (S-
protein) to recognize the receptor protein ACE2 of human cells and initiate infection, during …
protein) to recognize the receptor protein ACE2 of human cells and initiate infection, during …
Receptor binding may directly activate the fusion machinery in coronavirus spike glycoproteins
Y Wang, L Fallon, L Raguette, S Budhan, K Belfon… - bioRxiv, 2021 - biorxiv.org
Abstract SARS-CoV-2, the causative agent of the COVID-19 pandemic, is an enveloped
RNA virus. Trimeric spike glycoproteins extend outward from the virion; these class I viral …
RNA virus. Trimeric spike glycoproteins extend outward from the virion; these class I viral …
[PDF][PDF] Plant-Produced Glycosylated and In Vivo Deglycosylated Receptor Binding Domain Proteins of SARS-CoV-2 Induce Potent Neutralizing Responses in Mice …
The COVID-19 pandemic, caused by SARS-CoV-2, has rapidly spread to more than 222
countries and has put global public health at high risk. The world urgently needs cost …
countries and has put global public health at high risk. The world urgently needs cost …
Improving the Toolbox to Study Protein Dynamics and Conformational Analysis of Viral Proteins
KAA Belfon - 2021 - search.proquest.com
Protein dynamics describe the conformational changes in protein and play an essential role
in the function and evolution of proteins. Molecular dynamics (MD) can study protein …
in the function and evolution of proteins. Molecular dynamics (MD) can study protein …
[图书][B] Biophysical investigation of acyl-carrier and SARS-CoV-2 protein communication mechanisms
T Sztain-Pedone - 2021 - search.proquest.com
Proteins are one of the primary macromolecules that carry out the many essential functions
of life. They catalyze chemical reactions, provide structural integrity, and perform biological …
of life. They catalyze chemical reactions, provide structural integrity, and perform biological …
Composition and method to stabilize coronavirus spike glycoproteins in pre-fusion conformation
C Simmerling - US Patent App. 18/314,769, 2023 - Google Patents
Compositions include coronavirus S1/S2 prefusion spike proteins with specifically designed
disulfide bond that “staple” together the central helix and a region of the spike known as …
disulfide bond that “staple” together the central helix and a region of the spike known as …