Brain structure and function depend on a constant and sufficient supply with
eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) by blood. Blood levels of …

The prevalence of Alzheimer's disease (AD) continues to rise due to the increasing aging
population. Among the various genetic factors associated with AD, apolipoprotein E (ApoE) …

Long chain polyunsaturated omega-3 fatty acids (n-3 FA), such as eicosapentaenoic acid
(EPA) and docosahexaenoic acid (DHA), are known to be important components in a …

Although the human lifespan has increased in the past century owing to advances in
medicine and lifestyle, the human healthspan has not kept up the same pace, especially in …

The elderly population is growing at increased rates and is expected to double in size by
2050 in the United States and worldwide. The consumption of healthy foods and enriched …

Emerging evidence is showing nutrition as a crucial factor in the high prevalence and
incidence of neurodegenerative mental disorders. Preventive interventions on …

Both epidemiological and preclinical studies have shown the benefits of n-3 polyunsaturated
fatty acid (n-3 PUFA) on dementia and cognitive impairment, yet the results of clinical …

Purpose Vitamins and polyunsaturated fatty acids (PUFAs) have been studied extensively
as safe and manageable nutrient interventions for mild cognitive impairment (MCI). The …

Polyunsaturated fatty acids (PUFAs) are a class of fatty acids that are closely associated with
the development and function of the brain. The most abundant PUFA is docosahexaenoic …

Background: Mild cognitive impairment (MCI) is the prodromal stage of dementia. In this
stage, reasonable intervention measures can help to delay the decline of cognitive function …