Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas.
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …

Cardiovascular diseases (CVDs) are the leading cause of death in the industrialized world.
Most CVDs are associated with increased inflammation that arises mainly from innate …

Toll-like receptors (TLRs) have a critical role in the pathogenesis and disease course of viral
infections. The induced pro-inflammatory responses result in the disturbance of the …

Abdominal aortic aneurysm (AAA) is an inflammatory vascular disease with high disability
and mortality. Its susceptible risk factors include old age, being male, smoking, hypertension …

Endothelial cells (ECs) play a critical role in health and disease due to their widespread
distribution and unique location. Although ECs are not regarded as classical immune cells …

Retinoic acid-inducible gene I (RIG-I) is a cytosolic pattern recognition receptor that contains
two CARD domains, an RNA helicase domain, and a C-terminal domain. RIG-I initiates …

Background Abdominal aortic aneurysm (AAA), an irreversible cardiovascular disease
prevalent in the artery, causes the increase of the aneurysm diameter over time, and is a …

An abdominal aortic aneurysm (AAA) is a multifactorial disease with a variety of genetic and
environmental risk factors, but the exact mechanism of AAA formation and progression is still …

This Research Topic sought to ignite meaningful discussions and enhance our
understanding of the advancements and perspectives presented in selected articles from the …

Objective: Notch-1 is a signal regulatory protein with extensive effects in myeloid cells, but its
role in aneurysms remains to be fully clarified. In this study, therefore, the aneurysm mouse …