Renal interstitial fibrosis: mechanisms and evaluation : Current Opinion in Nephrology and
Hypertension Renal interstitial fibrosis: mechanisms and evaluation : Current Opinion in …

Interstitial fibrosis is a hallmark structural correlate of progressive and chronic kidney
disease. There remain many uncertainties about how to best measure interstitial fibrosis …

Interstitial fibrosis is an outcome measure of increasing importance in clinical trials of both
renal transplantation and native disease, but data on the comparative advantages of fibrosis …

Identifying factors that are predictive of allograft loss might be an important step toward
prolonging kidney allograft survival. In this study we sought to determine the association …

Background. Clinical trials in renal transplantation must use surrogate markers of long-term
graft survival if conclusions are to be drawn at acceptable speed and cost. Morphologic …

Proteinuria is associated with reduced kidney allograft survival. Herein we assessed the
association between proteinuria, graft histology and survival. The cohort included 613 …

Chronic allograft nephropathy (CAN) is a major problem in posttransplant management. The
lack of a reliable and early surrogate marker of CAN has hampered patient care and …

The hallmark of failing renal transplants is tubular atrophy and interstitial fibrosis (TA/IF).
Injury to tubular epithelial cells (TEC) could contribute to fibrogenesis via epithelial …

Some features of kidney transplants with dysfunction overlap the lesions of aging, such as
tubular atrophy and interstitial fibrosis (TA/IF) without major glomerular abnormalities …

Chronic allograft dysfunction (CAD), characterized histologically by interstitial fibrosis and
tubular atrophy, is the major cause of kidney allograft loss. Here, using single nuclei RNA …