[HTML][HTML] Emerging techniques in single-cell epigenomics and their applications to cancer research

PK Lo, Q Zhou - Journal of clinical genomics, 2018 - ncbi.nlm.nih.gov
Epigenomics encompasses studies of the chemical modifications of genomic DNA and
associated histones, interactions between genomic DNA sequences and proteins, the …

Neurochemical heterogeneity among lateral hypothalamic hypocretin/orexin and melanin-concentrating hormone neurons identified through single-cell gene …

LE Mickelsen, FW Kolling, BR Chimileski, A Fujita… - eneuro, 2017 - eneuro.org
The lateral hypothalamic area (LHA) lies at the intersection of multiple neural and humoral
systems and orchestrates fundamental aspects of behavior. Two neuronal cell types found in …

[HTML][HTML] Whole-body tracking of single cells via positron emission tomography

KO Jung, TJ Kim, JH Yu, S Rhee, W Zhao… - Nature biomedical …, 2020 - nature.com
In vivo molecular imaging can measure the average kinetics and movement routes of
injected cells through the body. However, owing to non-specific accumulation of the contrast …

Single-cell technologies in environmental omics

R Kodzius, T Gojobori - Gene, 2016 - Elsevier
Environmental studies are primarily done by culturing isolated microorganisms or by
amplifying and sequencing conserved genes. Difficulties understanding the complexity of …

μCB-seq: microfluidic cell barcoding and sequencing for high-resolution imaging and sequencing of single cells

TN Chen, A Gupta, MD Zalavadia, A Streets - Lab on a Chip, 2020 - pubs.rsc.org
Single-cell RNA sequencing (scRNA-seq) enables the investigation of complex biological
processes in multicellular organisms with high resolution. However, many phenotypic …

Isolation of MDCK cells with low expression of mdr1 gene and their use inmembrane permeability screening

A Bokulić, J Padovan… - Acta …, 2022 - hrcak.srce.hr
Sažetak The Madin-Darby canine kidney (MDCK) cell line is frequently used for permeability
screening in drug discovery. It contains endogenous transporters, most prominently canine …

Effect of antifreeze protein I in the freezing solution on in vivo-derived sheep embryos

LFL Correia, GR Leal, FZ Brandão, RITP Batista… - Research in Veterinary …, 2024 - Elsevier
This study evaluated the effects of different antifreeze protein type I (AFP I) concentrations
added to a slow freezing solution in sheep in vivo-derived embryos. Good-quality embryos …

Single-Cell PET Imaging and Tracking

KO Jung, G Pratx - Positron Emission Tomography: Methods and …, 2023 - Springer
Positron emission tomography (PET) is one of the most sensitive whole-body molecular
imaging techniques available in the clinic, able to detect picomolar levels of probe. As such …

Imaging the Tumor Antioxidant Response with [18F]FSPG PET

OV Timmermand, TH Witney - Positron Emission Tomography: Methods …, 2023 - Springer
Abstract (4S)-4-(3-[18F] Fluoropropyl)-L-glutamic acid ([18F] FSPG) is a flourine-18 labeled
glutamate analog that enables the noninvasive in vivo imaging of cellular redox status.[18F] …

Automated Immunomagnetic Enrichment and Optomicrofluidic Detection to Isolate Breast Cancer Cells: A Proof-of-Concept towards PoC Therapeutic Decision …

J Stiefel, M Baßler, J Wittek, C Freese - Magnetochemistry, 2022 - mdpi.com
In breast cancer research, immunomagnetic enrichment of circulating tumor cells (CTCs)
from body fluids has impressively evolved over the last decades. However, there is growing …