In recent years, there has been a great deal of progress toward understanding the role of the
striatum and dopamine in action selection. The advent of new animal models and the …

Parkinson's disease (PD) is a multi-systemic neurodegenerative brain disorder. Motor
symptoms of PD are linked to the significant dopamine (DA) loss in substantia nigra pars …

Sparse, sequential patterns of neural activity have been observed in numerous brain areas
during timekeeping and motor sequence tasks. Inspired by such observations, we construct …

Dystonia is a functionally disabling movement disorder characterized by abnormal
movements and postures. Although substantial recent progress has been made in …

Multi-recording techniques show evidence that neurons coordinate their firing forming
ensembles and that brain networks are made by connections between ensembles. While …

A major advance in understanding learning behavior stems from experiments showing that
reward learning requires dopamine inputs to striatal neurons and arises from synaptic …

The basal ganglia have been hypothesized to be involved in action selection, ie resolving
competition between simultaneously activated motor programs. It has been shown that the …

Reservoir computing is a brain-inspired machine learning framework for processing
temporal data by mapping inputs into high-dimensional spaces. Physical reservoir …

There is no hypothesis to explain how direct and indirect basal ganglia (BG) pathways
interact to reach a balance during the learning of motor procedures. Both pathways …

Dopamine (DA) modulates glutamatergic synaptic transmission and its plasticity in the
striatum; however it is not well known how DA modulates long‐term plasticity of striatal …