[HTML][HTML] Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements
Diverse inbred mouse strains are important biomedical research models, yet genome
characterization of many strains is fundamentally lacking in comparison with humans. In …
characterization of many strains is fundamentally lacking in comparison with humans. In …
Utilizing preclinical models of genetic diversity to improve translation of phytochemical activities from rodents to humans and inform personalized nutrition
L Iglesias-Carres, AP Neilson - Food & Function, 2021 - pubs.rsc.org
Mouse models are an essential tool in different areas of research, including nutrition and
phytochemical research. Traditional inbred mouse models have allowed the discovery of …
phytochemical research. Traditional inbred mouse models have allowed the discovery of …
Stability of quercetin in DMEM and cell culture with A549 cells
Quercetin is evidently unstable in Dulbecco's modified Eagle's medium (DMEM) at 37° C.
However, the underlying mechanism of this instability is not clear yet. The stability and new …
However, the underlying mechanism of this instability is not clear yet. The stability and new …
Water extract of Ferula lehmanni Boiss. prevents high-fat diet-induced overweight and liver injury by modulating the intestinal microbiota in mice
Y Ye, L Shi, P Wang, M Yang, P Zhan, H Tian, J Liu - Food & function, 2022 - pubs.rsc.org
Obesity, often accompanied by hepatic steatosis, has been associated with an increased
risk of health complications such as fatty liver disease and certain cancers. Ferula lehmannii …
risk of health complications such as fatty liver disease and certain cancers. Ferula lehmannii …
[HTML][HTML] Dexamethasone-induced muscle atrophy and bone loss in six genetically diverse collaborative cross founder strains demonstrates phenotypic variability by …
BN Nguyen, S Hong, S Choi, CG Lee, GH Yoo… - Journal of Ginseng …, 2024 - Elsevier
Background Osteosarcopenia is a common condition characterized by the loss of both bone
and muscle mass, which can lead to an increased risk of fractures and disability in older …
and muscle mass, which can lead to an increased risk of fractures and disability in older …
Microbial metabolites of flavanols in urine are associated with enhanced anti-proliferative activity in bladder cancer cells in vitro
Flavanols are metabolized by the gut microbiota to bioavailable metabolites, and the
absorbed fraction is excreted primarily via urine. Uroepithelial cells are thus a potential site …
absorbed fraction is excreted primarily via urine. Uroepithelial cells are thus a potential site …
Effects of Green Apple (Golden Delicious) and Its Three Major Flavonols Consumption on Obesity, Lipids, and Oxidative Stress in Obese Rats
I Selek Aksoy, S Otles - Molecules, 2022 - mdpi.com
Obesity is becoming increasingly common all over the world and global strategies are
accordingly being developed to prevent it. In order to support the strategies, the effects of …
accordingly being developed to prevent it. In order to support the strategies, the effects of …
Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study
KC Racine, L Iglesias-Carres, JA Herring… - Biochemical and …, 2022 - Elsevier
Abstract Type 2 diabetes (T2D) is characterized by hyperglycemia and insulin resistance.
Cocoa may slow T2D development and progression. This study employed male and female …
Cocoa may slow T2D development and progression. This study employed male and female …
Journal of Nutritional Biochemistry Special Issue: Polyphenols, obesity, and cardiometabolic health
The first published research relating to polyphenols potentially occurred in the early 1920s
(Fig. 1). Research in this area remained relatively sparse throughout most of the 20th …
(Fig. 1). Research in this area remained relatively sparse throughout most of the 20th …
[图书][B] Protective Effects of Cocoa Flavanols Against Obesity and Type 2 Diabetes Are Influenced by Biological Sex and Host Gut Microbiome Composition
KC Racine - 2022 - search.proquest.com
Cocoa (Theobroma cacao) is a concentrated source of flavanols, which may provide
beneficial health activities. Flavanols can be classified by their degree of polymerization …
beneficial health activities. Flavanols can be classified by their degree of polymerization …