[HTML][HTML] The composition, pharmacological effects, related mechanisms and drug delivery of alkaloids from Corydalis yanhusuo

J Feng, K Chen, S Shen, Y Luo, X Liu, X Chen… - Biomedicine & …, 2023 - Elsevier
Corydalis yanhusuo WT Wang, also known as yanhusuo, yuanhu, yanhu and xuanhu, is one
of the herb components of many Chinese Traditional Medicine prescriptions such as Jin …

Berberine: a promising treatment for neurodegenerative diseases

Z Cheng, C Kang, S Che, J Su, Q Sun, T Ge… - Frontiers in …, 2022 - frontiersin.org
Berberine, as a natural alkaloid compound, is characterized by a diversity of
pharmacological effects. In recent years, many researches focused on the role of berberine …

Therapeutic efficacies of berberine against neurological disorders: an update of pharmacological effects and mechanisms

JW Shou, PC Shaw - Cells, 2022 - mdpi.com
Neurological disorders are ranked as the leading cause of disability and the second leading
cause of death worldwide, underscoring an urgent necessity to develop novel …

Research progress of plant‐derived natural alkaloids in central nervous system diseases

Q Zhang, Q Jiang, K Sa, J Liang, D Sun… - Phytotherapy …, 2023 - Wiley Online Library
Central nervous system (CNS) disease is one of the most important causes of human death.
Because of their complex pathogenesis, more and more attention has been paid to them. At …

Goofballing of opioid and methamphetamine: The science behind the deadly cocktail

HM Hazani, I Naina Mohamed, M Muzaimi… - Frontiers in …, 2022 - frontiersin.org
Globally, millions of people suffer from various substance use disorders (SUD), including
mono-and polydrug use of opioids and methamphetamine. Brain regions such as the …

Obeticholic acid protects against methamphetamine-induced anxiety-like behavior by ameliorating microbiota-mediated intestinal barrier impairment

JZ Yang, KK Zhang, JT He, LJ Chen, JF Ding, JL Liu… - Toxicology, 2023 - Elsevier
Methamphetamine (Meth) abuse can cause severe anxiety disorder and interfere with gut
homeostasis. Obeticholic acid (OCA) has emerged as a protective agent against diet-related …

(-)-α-bisabolol exerts neuroprotective effects against pentylenetetrazole-induced seizures in rats by targeting inflammation and oxidative stress

D Nazarinia, A Moslehi, P Hashemi - Physiology & Behavior, 2023 - Elsevier
Epilepsy is the most common neurological disorder which is accompanied with behavioral
and psychiatric alternations. Current evidences have shown that (-)-α-bisabolol (BSB) …

Repeated oxytocin treatment during abstinence inhibited context-or restraint stress-induced reinstatement of methamphetamine-conditioned place preference and …

J Cai, X Che, T Xu, Y Luo, M Yin, X Lu, C Wu… - Experimental …, 2022 - Elsevier
Propensity to relapse, even after long-term abstinence, is a crucial feature of
methamphetamine (METH) abuse. We and other laboratories have reported that acute …

Current evidence and future directions of berberine intervention in depression

WQ Zhu, HY Wu, ZH Sun, Y Guo, TT Ge, BJ Li… - Frontiers in …, 2022 - frontiersin.org
A major type of serious mood disorder, depression is currently a widespread and easily
overlooked psychological illness. With the low side effects of natural products in the …

Effects of berberine hydrochloride on left ventricular structure and function in rats with myocardial hypertrophy

T Kou, H Luo, Y Shen, Y Su, L Yin - Acta Cardiologica, 2023 - Taylor & Francis
Abstract Background Inhibition of Rho/ROCK signalling pathway related proteins can
alleviate left ventricular hypertrophy. Berberine hydrochloride (BBR) can effectively inhibit …