Classic theories of stress and health are largely based on assumptions regarding how
different psychosocial stressors influence biological processes that, in turn, affect human …

Abstract Background The Adverse Childhood Experiences International Questionnaire (ACE-
IQ) collects additional data (eg, witness community violence/terrorism) than the previous …

Early-life psychosocial stress primes a number of health risk behaviors, and contributes to
the development of various mental and somatic disorders in adulthood. It has been reported …

Physiological and psychological stressors can exert wide-ranging effects on the human
brain and behavior. Research has improved understanding of how the sympatho-adreno …

Surveys report that about three-quarters of visits to general practitioners in America are for
stress-related complaints. Animal and human studies have consistently demonstrated that …

Objective Childhood trauma may contribute to poor lifelong health in part through
programming of the HPA-axis response to future life stressors. To date, empirical evidence …

Background and Objectives A wealth of research has identified adverse childhood
experiences (ACEs; abuse, neglect, violence or disorder in the home) as a strong risk factor …

Background Early life stress (ELS) is associated with increased morbidity and mortality
across the lifecourse. Studies observing a relationship between ELS and stress physiology …

Adverse childhood experiences (ACEs) should be considered as context for assessment
and diagnosis of depression, anxiety, and behavioral problems for youth aged 0–18. The …

Despite decades of stress research, there still exist substantial gaps in our understanding of
how social, environmental, and biological factors interact and combine with developmental …