Background Post-acute sequelae of COVID-19 (PASC), also now known as long COVID,
has become a major global health and economic burden. Previously, we provided evidence …

It is becoming evident that B-cell responses to particular epitopes or in particular contexts
can be highly convergent at the molecular level. That is, depending on the epitope targeted …

The engagement of the B cell receptor (BcR) on the surface of leukemic cells represents a
key event in chronic lymphocytic leukemia (CLL) since it can lead to the maintenance and …

Chronic lymphocytic leukemia (CLL) is characterized by the existence of subsets of patients
with (quasi) identical, stereotyped B-cell receptor (BcR) immunoglobulins. Patients in certain …

The chronic lymphocytic leukemia (CLL) immunoglobulin repertoire is biased and
characterized by the existence of subsets of cases with closely homologous (“stereotyped”) …

The concept of precision cell therapy targeting tumor-specific mutations is appealing but
requires surface-exposed neoepitopes, which is a rarity in cancer. B cell receptors (BCR) of …

In recent years, determination of the mutational status of rearranged immunoglobulin heavy
chain variable (IGHV) genes in large series of patients with chronic lymphocytic leukaemia …

B cell chronic lymphocytic leukemia (CLL), the most common leukemia in adults, is a clonal
expansion of CD5+ CD19+ B lymphocytes. Two types of CLLs are being distinguished as …

Leukemic B lymphocytes of a large group of unrelated chronic lymphocytic leukemia (CLL)
patients express an unmutated heavy chain immunoglobulin variable (V) region encoded by …

The prognosis of chronic lymphocytic leukemia (CLL) depends on different markers,
including cytogenetic aberrations, oncogenic mutations, and mutational status of the …