Genomic imprinting, the monoallelic and parent-of-origin-dependent expression of a subset
of genes, is required for normal development, and its disruption leads to human disease …

Hydatidiform moles are intriguing pathologic entities representing abnormal placental villous
tissue with unique genetic profiles and a wide spectrum of morphologic features, which …

Background Genomic imprinting results from the resistance of germline epigenetic marks to
reprogramming in the early embryo for a small number of mammalian genes. Genetic …

Nucleotide‐binding oligomerization domain (NOD) and leucine‐rich repeat (LRR)‐
containing receptors or NOD‐like receptors (NLRs) are cytosolic pattern recognition …

Imprinting disorders (ImpDis) are a group of currently 12 congenital diseases with common
underlying (epi) genetic etiologies and overlapping clinical features affecting growth …

The abnormal pregnancies complete and partial hydatidiform mole are genetically unusual,
being associated with two copies of the paternal genome. Typical complete hydatidiform …

Genomic imprinting is an epigenetic marking process that results in the monoallelic
expression of a subset of genes. Many of these 'imprinted'genes in mice and humans are …

DNA methylation is globally reprogrammed after fertilization, and as a result, the parental
genomes have similar DNA-methylation profiles after implantation except at the germline …

De novo DNA methylation (DNAme) during mouse oogenesis occurs within transcribed
regions enriched for H3K36me3. As many oocyte transcripts originate in long terminal …

Maternal effect genes (MEGs) encode factors (eg, RNA) that are present in the oocyte and
required for early embryonic development. Hence, while these genes and gene products are …