[HTML][HTML] RNA granules in neuronal plasticity and disease

KE Bauer, BR de Queiroz, MA Kiebler, F Besse - Trends in Neurosciences, 2023 - cell.com
RNA granules are dynamic entities controlling the spatiotemporal distribution and translation
of RNA molecules. In neurons, a variety of RNA granules exist both in the soma and in …

Adipose exosomal noncoding RNAs: Roles and mechanisms in metabolic diseases

YL Wu, ZJ Lin, CC Li, X Lin, SK Shan, B Guo… - Obesity …, 2024 - Wiley Online Library
Exosomes are extracellular vesicles, measuring 40–160 nm in diameter, that are released
by many cell types and tissues, including adipose tissue. Exosomes are critical mediators of …

The lncRNA Malat1 is trafficked to the cytoplasm as a localized mRNA encoding a small peptide in neurons

W Xiao, R Halabi, CH Lin, M Nazim… - Genes & …, 2024 - genesdev.cshlp.org
Synaptic function in neurons is modulated by local translation of mRNAs that are transported
to distal portions of axons and dendrites. The metastasis‐associated lung adenocarcinoma …

[HTML][HTML] LncRNA TubAR complexes with TUBB4A and TUBA1A to promote microtubule assembly and maintain myelination

X Liang, M Gong, Z Wang, J Wang, W Guo, A Cai… - Cell Discovery, 2024 - nature.com
A long-standing hypothesis proposes that certain RNA (s) must exhibit structural roles in
microtubule assembly. Here, we identify a long noncoding RNA (TubAR) that is highly …

[HTML][HTML] Enhancers are genes that express organizational RNAs

JS Mattick - Frontiers in RNA Research, 2023 - frontiersin.org
A longstanding enigma in molecular biology is the lack of scaling of protein-coding genes
with developmental complexity, referred to as the g-value paradox. On the other hand, a …

[HTML][HTML] Me31B: a key repressor in germline regulation and beyond

M Gao - Bioscience Reports, 2024 - portlandpress.com
Abstract Maternally Expressed at 31B (Me31B), an evolutionarily conserved ATP-dependent
RNA helicase, plays an important role in the development of the germline across diverse …

ELAV mediates circular RNA biogenesis in neurons

C Alfonso-Gonzalez, S Holec, S Gorey, M Shi, M Rauer… - bioRxiv, 2024 - biorxiv.org
Circular RNAs (circRNAs) arise from back-splicing of precursor RNAs and accumulate in the
nervous system of animals, where they are thought to regulate gene expression and …