Supervised machine learning for population genetics: a new paradigm
DR Schrider, AD Kern - Trends in Genetics, 2018 - cell.com
As population genomic datasets grow in size, researchers are faced with the daunting task
of making sense of a flood of information. To keep pace with this explosion of data …
of making sense of a flood of information. To keep pace with this explosion of data …
Fitness, growth and transmissibility of SARS-CoV-2 genetic variants
E Volz - Nature Reviews Genetics, 2023 - nature.com
The massive scale of the global SARS-CoV-2 sequencing effort created new opportunities
and challenges for understanding SARS-CoV-2 evolution. Rapid detection and assessment …
and challenges for understanding SARS-CoV-2 evolution. Rapid detection and assessment …
PopGenome: an efficient Swiss army knife for population genomic analyses in R
B Pfeifer, U Wittelsbürger… - Molecular biology …, 2014 - academic.oup.com
Although many computer programs can perform population genetics calculations, they are
typically limited in the analyses and data input formats they offer; few applications can …
typically limited in the analyses and data input formats they offer; few applications can …
DnaSP, DNA polymorphism analyses by the coalescent and other methods
J Rozas, JC Sánchez-DelBarrio, X Messeguer… - …, 2003 - academic.oup.com
DnaSP is a software package for the analysis of DNA polymorphism data. Present version
introduces several new modules and features which, among other options allow:(1) …
introduces several new modules and features which, among other options allow:(1) …
Molecular signatures of natural selection
R Nielsen - Annu. Rev. Genet., 2005 - annualreviews.org
There is an increasing interest in detecting genes, or genomic regions, that have been
targeted by natural selection. The interest stems from a basic desire to learn more about …
targeted by natural selection. The interest stems from a basic desire to learn more about …
The unreasonable effectiveness of convolutional neural networks in population genetic inference
L Flagel, Y Brandvain… - Molecular biology and …, 2019 - academic.oup.com
Population-scale genomic data sets have given researchers incredible amounts of
information from which to infer evolutionary histories. Concomitant with this flood of data …
information from which to infer evolutionary histories. Concomitant with this flood of data …
Nationwide genomic atlas of soil-dwelling Listeria reveals effects of selection and population ecology on pangenome evolution
Natural bacterial populations can display enormous genomic diversity, primarily in the form
of gene content variation caused by the frequent exchange of DNA with the local …
of gene content variation caused by the frequent exchange of DNA with the local …
Soft sweeps are the dominant mode of adaptation in the human genome
DR Schrider, AD Kern - Molecular biology and evolution, 2017 - academic.oup.com
The degree to which adaptation in recent human evolution shapes genetic variation remains
controversial. This is in part due to the limited evidence in humans for classic “hard selective …
controversial. This is in part due to the limited evidence in humans for classic “hard selective …
Genetic analyses of atypical Toxoplasma gondii strains reveal a fourth clonal lineage in North America
Toxoplasma gondii is a widespread parasite of animals that causes zoonotic infections in
humans. Previous studies have revealed a strongly clonal population structure in North …
humans. Previous studies have revealed a strongly clonal population structure in North …
Linkage disequilibrium as a signature of selective sweeps
The hitchhiking effect of a beneficial mutation, or a selective sweep, generates a unique
distribution of allele frequencies and spatial distribution of polymorphic sites. A composite …
distribution of allele frequencies and spatial distribution of polymorphic sites. A composite …