Much effort has gone into the immobilization of homogeneous catalysts based on the idea
that in this way the catalysts could be not only separated more easily from the product but …

Asymmetric hydrogenations are increasingly being used to introduce stereogenic centres
into products used in the life sciences industries. There are a number of potential pitfalls …

This Account provides an overview of our activities in the area of asymmetric hydrogenation
over the last 12 years. We discuss the manufacture of metal-containing precatalysts and …

This work explores the potential of iridium complexes of the N-heterocyclic carbene
oxazoline ligands 1 in asymmetric hydrogenations of arylalkenes. The accessible carbene …

Attempts are made to define the" ideal synthesis"," ideal catalyst", and" ideal recoverable
catalyst". Although these unattainable limits can never be realized, they help to focus …

Whereas recent synthetic studies concerning Rh-catalyzed olefin hydrogenation based on
BINOL-derived monodentate phosphites have resulted in an efficient and economically …

A convenient synthesis of new chiral phosphine− phosphites (P− OP) has been described.
The versatility of the synthetic protocol developed has allowed the preparation of ligands …

Transition-metal-complex-catalyzed asymmetric hydrogenation of archetypal β-amido β-
(methyl or phenyl) acrylates (and close derivatives) into the corresponding enantioenriched …

Transient behavior at the beginning of homogeneous catalytic reactions is a common
phenomenon, since the active catalytic species is often formed under reaction conditions. If …

This contribution gives an overview of the synthesis of chiral β-amino acids via asymmetric
hydrogenation of the corresponding dehydroamino derivatives. Literature results are …