A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …

During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

Several vaccines against COVID-19 use nanoparticles to protect the antigen cargo (either
proteins or nucleic acids), increase the immunogenicity and ultimately the efficacy. The …

Background Vaccines are urgently needed to prevent the global spread of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). We assessed the safety and …

SARS-CoV-2 mRNA vaccines have demonstrated high efficacy and immunogenicity, but
limited information is currently available on memory B cell generation and long-term …

Sewer overflow (SO), which has attracted global attention, poses serious threat to public
health and ecosystem. SO impacts public health via consumption of contaminated drinking …

In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

Development of safe and effective COVID-19 vaccines is a global priority and the best hope
for ending the COVID-19 pandemic. Remarkably, in less than 1 year, vaccines have been …

Aging is characterized by the dynamic remodeling of the immune system designated
“immunosenescence,” and is associated with altered hematopoiesis, thymic involution, and …

A year after the initial outbreak of Covid-19 pandemic, several Phase III clinical trials
investigating vaccine safety and efficacy have been published. These vaccine candidates …