Mitogen signaling strength and duration can control cell cycle decisions

R Nussinov, W Zhang, Y Liu, H Jang - Science Advances, 2024 - science.org
Decades ago, mitogen-promoted signaling duration and strength were observed to be
sensed by the cell and to be critical for its decisions: to proliferate or differentiate. Landmark …

[HTML][HTML] Mechanosensitive Piezo1 channel in physiology and pathophysiology of the central nervous system

B Zong, F Yu, X Zhang, Y Pang, W Zhao, P Sun… - Ageing Research …, 2023 - Elsevier
Since the discovery of the mechanosensitive Piezo1 channel in 2010, there has been a
significant amount of research conducted to explore its regulatory role in the physiology and …

Epigenetic maintenance of adult neural stem cell quiescence in the mouse hippocampus via Setd1a

T Zhao, Y Hong, B Yan, S Huang, G Ming… - Nature …, 2024 - nature.com
Quiescence, a hallmark of adult neural stem cells (NSCs), is required for maintaining the
NSC pool to support life-long continuous neurogenesis in the adult dentate gyrus (DG) …

Selection against domestication alleles in introduced rabbit populations

P Andrade, JM Alves, P Pereira, CJ Rubin… - Nature ecology & …, 2024 - nature.com
Humans have moved domestic animals around the globe for thousands of years. These
have occasionally established feral populations in nature, often with devastating ecological …

Epigenetic regulation in adult neural stem cells

J Shi, Z Wang, Z Wang, G Shao, X Li - Frontiers in Cell and …, 2024 - frontiersin.org
Neural stem cells (NSCs) exhibit self-renewing and multipotential properties. Adult NSCs
are located in two neurogenic regions of adult brain: the ventricular-subventricular zone (V …

Transcriptional control of neural stem cell activity

T Kaise, R Kageyama - Biochemical Society Transactions, 2024 - portlandpress.com
In the adult brain, neural stem cells (NSCs) are under the control of various molecular
mechanisms to produce an appropriate number of neurons that are essential for specific …